Results 151 to 160 of about 120,627 (303)

The Role of Histone Methyltransferase SETDB1 in Normal and Malignant Hematopoiesis

Cancer Science, EarlyView.
In this review, we discuss the role of SETDB1 in gene regulation, including an overview of its structural features and key cofactors. We also highlight the lineage‐specific roles of SETDB1 in both normal hematopoietic processes and hematological malignancies, emphasizing its function as an immune checkpoint molecule that suppresses natural killer cell ...
Yu‐Hsuan Chang, Susumu Goyama
wiley   +1 more source

Association of endogenous retroviruses with radiation-induced leukemias of BALB/c mice [PDF]

, 1980
Ronald W. Ellis, Elisabeth Stockert, E Fleissner   +2 more
openalex   +1 more source

Discovery of Novel RASGRF2 Fusions as a Therapeutic Target in Lung Adenocarcinoma of Never or Light Smokers

Cancer Science, EarlyView.
This study discovered actionable novel fusions of RASGRF1 and RASGRF2 in lung adenocarcinoma of never‐smoker and identified that those fusions transformed the cells through phosphorylation of MEK, which was inhibited by cobimetinib treatment. A risk score based on the four‐gene signature could predict the prognosis of surgically resected lung ...
Yuki Terashima, Soohwan Park, Hiroshi Ikeuchi, Takuo Hayashi, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Yoshiyuki Suehara, Shinya Tanaka, Kenji Suzuki, Hiroyuki Mano, Kazuya Takamochi, Shinji Kohsaka   +13 more
wiley   +1 more source

Interspecies radioimmunoassay for the major structural proteins of primate type-D retroviruses.

, 1977
David Colcher, Y A Teramoto, Jeffrey Schlom   +2 more
openalex   +1 more source

Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. [PDF]

, 1986
Parmjit Jat, Constance L. Cepko, Richard C. Mulligan, Phillip A. Sharp   +3 more
openalex   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Biocommunication of Fungal Organisms [PDF]

, 2008
The development and growth of fungal organisms depend on successful communication processes (a) within the organism and between organisms, (b) with the same or related species and (c) with non-related organisms.
Guenther Witzany
core   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

Cell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou, Chen Gao, Wenxuan Zhao, Xinhua Wei, Dawei Yu, Huiying Zou, Weihua Du   +6 more
wiley   +1 more source

Role of the Psi Packaging Signal and Dimerization Initiation Sequence in the Organization of Rous Sarcoma Virus Gag-gRNA Co-Condensates

Viruses
Retroviral genome selection and virion assembly remain promising targets for novel therapeutic intervention. Recent studies have demonstrated that the Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type-1 (HIV-1) undergo ...
Gregory S. Lambert, Rebecca J. Kaddis Maldonado, Leslie J. Parent   +2 more
doaj   +1 more source

Amino-terminal amino acid sequence of the major structural polypeptides of avian retroviruses: sequence homology between reticuloendotheliosis virus p30 and p30s of mammalian retroviruses.

, 1978
Eric Hunter, Ajit S. Bhown, J. Bennett
openalex   +1 more source