Results 151 to 160 of about 124,737 (275)

Retroviruses integrate into a shared, non-palindromic motif [PDF]

, 2015
Paul Kirk, Maxime Huvet, Anat Melamed, Goedele N. Maertens, Charles R. M. Bangham   +4 more
openalex   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source

Heparanase, a host gene that potently restricts retrovirus transcription

mBio
Heparanase (HPSE) is a heterodimeric β-D-glucuronidase that is critical in mammalian cells for the enzymatic cleavage of membrane-associated heparan sulfate moieties.
Brandon Waxman, Kyle Salka, Uddhav Timilsina, Supawadee Umthong, Deepak Shukla, Spyridon Stavrou   +5 more
doaj   +1 more source

Human endogenous retroviruses and cancer: Causality and therapeutic possibilities

, 2012
Christina Susanne Mullins
openalex   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Role of the Psi Packaging Signal and Dimerization Initiation Sequence in the Organization of Rous Sarcoma Virus Gag-gRNA Co-Condensates

Viruses
Retroviral genome selection and virion assembly remain promising targets for novel therapeutic intervention. Recent studies have demonstrated that the Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type-1 (HIV-1) undergo ...
Gregory S. Lambert, Rebecca J. Kaddis Maldonado, Leslie J. Parent   +2 more
doaj   +1 more source

Process Systems Engineering in Precision Medicine: Opportunities in Autologous CAR‐T Therapy

Engineering in Life Sciences, Volume 26, Issue 2, February 2026.
ABSTRACT Autologous chimeric antigen receptor (CAR)‐T therapies have given hope to many cancer patients whose other lines of treatment have failed. Unfortunately, limited manufacturing capability has resulted in many patients dying while on a waitlist.
B. Wayne Bequette
wiley   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source

Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva, Petra Junková, Ondřej Vaněk, Zuzana Jalovcová, Ivana Křížová, Alžběta Dostálková, Michaela Rumlová   +6 more
wiley   +1 more source

Infectious entry of murine retroviruses into mouse cells: evidence of a postadsorption step inhibited by acidic pH [PDF]

, 1985
John L. Portis, Frank J. McAtee, Leonard H. Evans   +2 more
openalex   +1 more source