Results 121 to 130 of about 2,676,768 (277)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Hyper-resolution flood hazard mapping at the national scale [PDF]

Natural Hazards and Earth System Sciences
Flood hazard mapping is currently in a transitional phase involving the use of data and methods that were traditionally in the domain of local studies in a regional or nationwide context. Challenges include the representation of local information such as
G. Blöschl, A. Buttinger-Kreuzhuber, A. Buttinger-Kreuzhuber, D. Cornel, J. Eisl, M. Hofer, M. Hollaus, Z. Horváth, Z. Horváth, J. Komma, A. Konev, J. Parajka, N. Pfeifer, A. Reithofer, J. Salinas, J. Salinas, P. Valent, R. Výleta, J. Waser, M. H. Wimmer, H. Stiefelmeyer   +20 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Determination of the reinforced concrete slabs ultimate load using finite element method and mathematical programming

Latin American Journal of Solids and Structures
In the present paper, the ultimate load of the reinforced concrete slabs [16] is determined using the finite element method and mathematical programming.
A.M. Mont'Alverne, E.P. Deus, S.C. Oliveira Junior, A.S. Moura   +3 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Localization and Fluctuations in Quantum Kicked Rotors

, 1999
We address the issue of fluctuations, about an exponential lineshape, in a pair of one-dimensional kicked quantum systems exhibiting dynamical localization.
Ketoja, Jukka A., Satija, Indubala I., Sundaram, Bala   +2 more
core   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Return migration and embedding: through the lens of Brexit as an unsettling event

Comparative Migration Studies
This introductory paper, reflecting the Thematic Cluster of four papers, brings together two themes that are important for migration studies: return migration and embedding.
Izabela Grabowska, Louise Ryan
doaj   +1 more source

Application of a regional approach for hazard mapping at an avalanche site in northern Italy [PDF]

Advances in Geosciences, 2008
The currently adopted approach to avalanche hazard mapping in northern Italy includes avalanche dynamic modelling, coupled with statistical analysis of snow depth at avalanche start. The 30-years and 300-years return period avalanches at a given site are
D. Bocchiola, R. Rosso
doaj