Results 101 to 110 of about 2,676,768 (277)

Out-of-plane dynamic response of a tuff masonry wall. Shaking table testing and numerical simulation [PDF]

open access: yes, 2017
The out-of-plane dynamic response of a masonry element is investigated, both experimentally and numerically. The results of shaking table tests on a tuff masonry wall, subjected to harmonic acceleration histories, are presented.
Addessi, Daniela   +3 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Flood volume allocation method for flood hazard mapping using river model with levee scheme [PDF]

open access: yesGeoscientific Model Development
A realistic flood risk assessment is important for rivers where the flood protection infrastructures are dictated by varying return periods. For rivers in Japan, design return periods for flood protection infrastructures range up to 200 years.
M. H. Aslam   +6 more
doaj   +1 more source

Numerical modeling of strain rate hardening effects on viscoplastic behavior of metallic materials [PDF]

open access: yes, 2017
The main goal of the present work is to provide a finite strain elasticviscoplastic framework to numerically account for strain, strain rate hardening, and viscous effects in cold deformation of metallic materials. The aim is to provide a simple and robust
Dos Santos, Tiago   +3 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Mapping Wildfire Ignition Probability Using Sentinel 2 and LiDAR (Jerte Valley, Cáceres, Spain)

open access: yesSensors, 2018
Wildfire is a major threat to the environment, and this threat is aggravated by different climatic and socioeconomic factors. The availability of detailed, reliable mapping and periodic and immediate updates makes wildfire prevention and extinction work ...
Yolanda Sánchez Sánchez   +3 more
doaj   +1 more source

An efficient numerical method for shakedown analysis [PDF]

open access: yes, 2013
The algorithm proposed in [9] for incremental elastoplasticity is extended and applied to shakedown analysis. Using the three field mixed finite element proposed in [22] a series of mathematical programming problems or steps, obtained from the application
Bilotta, A., Garcea, G., Leonetti, L.
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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