Results 41 to 50 of about 63,331,322 (298)

Protocol of a randomized controlled trial on the effectiveness and cost-effectiveness of the PLACES intervention: a supported employment intervention aimed at enhancing work participation of unemployed and/or work-disabled cancer survivors

Trials
Background Approximately onethird of cancer survivors encounter challenges reintegrating into the workforce, often experiencing involuntary unemployment and/or partial or full work disability following diagnosis and treatment.
F. van Ommen, S. F. A. Duijts, P. Coenen, S. O. Dalton, A. Kliffen, R. van Hummel, A. G. E. M. de Boer, M. A. Greidanus   +7 more
doaj   +1 more source

Theoretical perspectives upon the return to work of cancer patients: The difficult path of integration in the organization

Social Change Review, 2015
The present article follows an in-depth analysis of several relevant articles and major findings concerning the return to work of cancer patients, in various situations, from a manager and patient point of view, putting into discussion the effects and ...
Popa Radu-Ioan
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Return to normal activity after abdominal surgery: a pre-planned secondary analysis of a randomised controlled trial across seven low- and middle-income countries

BMC Surgery
Background Recovery after major surgery is a key priority identified by patients, communities and policymakers in low- and middle-income countries (LMICs), with important societal and financial implications. With global burden of surgical diseases rising,
Omar Omar, Sivesh Kathir Kamarajah
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Resumption of Employment after Cervical Cancer Surgery: a 3-Year Follow-Up Study of Long-term Outcomes [PDF]

Вестник восстановительной медицины
INTRODUCTION. Despite advancements in cervical cancer (CC) diagnosis and treatment, surgical intervention remains the cornerstone of radical treatment. However, surgical procedures can result in complications such as lymphedema, sexual dysfunction, and ...
Dmitry V. Blinov, Antonina G. Solopova, Elena V. Gameeva, Nazim G. Badalov, Mikhail A. Eremushkin, Alexandra M. Stepanova, Vsevolod N. Galkin, Alexander E. Ivanov, Saida A Akavova   +8 more
doaj   +1 more source

Return to work revisited [PDF]

, 2009
Being out of work can have harmful effects on both physical and mental health, and nobody wants to hear that they are too ill to work. Yet the number of people on incapacity benefit (IB) has more than trebled since the 1970s to 2.7 million (DWP, 2002 ...
Fear, William J.
core  

Consumer perspectives of vocational rehabilitation and return to work following acquired brain injury

, 2021
Introduction: Following acquired brain injury, the goal of return to work is common. While return to work is supported through different rehabilitation models and services, access to vocational rehabilitation varies within and between countries, and ...
Ehlers, S, Murray, A, Mclennan, V, Nielsen, M, Kennedy, A, Vogler, J, Jeffery, S, Watter, K   +7 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Exploring factors relevant in the assessment of the return-to-work process of employees on long-term sickness absence due to a depressive disorder: a focus group study [PDF]

, 2012
Background: Efforts undertaken during the Return-to-Work (RTW) process need to be sufficient in order to optimize the quality of the RTW process. The purpose of this study was to explore factors relevant to Return-to-Work Effort Sufficiency (RTW-ES) in ...
Brouwer, S., Muijzer, A., Groothoff Johan W, Brouwer, Sandra, Muijzer, Anna, Brouwer Sandra, Geertzen, Jan H.; id_orcid, Groothoff, J.W., Geertzen, Jan H., Muijzer Anna, Geertzen, J.H., Geertzen Jan H, Groothoff, Johan W.   +12 more
core   +1 more source