Results 81 to 90 of about 671,235 (265)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Return to Education in Malaysia
International Journal of Management Studies, 2009 The aim of this paper is to present a picture of return to education in Malaysia over the period from 1984 to 1997 based on earning equations model. The paper employed a set of data comprising micro-level data from the Household Income Survey (HIS) for ...
Rusmawati Said +2 more
doaj +3 more sources
The short-term intermittency evaluation of distributed photovoltaic power
HeliyonUncertainty of distributed photovoltaic(PV) power brings great challenges to the safe and stable operation of power system, in which the intermittency problem is more challenging than the fluctuation.
Yili Ma, Yi Huang, Yue Yuan
doaj +1 more source
Changes of Extreme Sea Level in 1.5 and 2.0°C Warmer Climate Along the Coast of China
Frontiers in Earth Science, 2018 Using hourly sea level data from 15 tide gauges along the Chinese coast and sea level data of three simulations of the Coupled Model Intercomparison Project Phase 5 (CMIP5), we assessed the changes and benefits of the extreme sea level of limiting ...
Jianlong Feng +6 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
KINERJA KEUANGAN KONVENSIONAL, ECONOMIC VALUE ADDED, DAN RETURN SAHAM
Jurnal Dinamika Manajemen, 2011 Penelitian ini bertujuan untuk menguji pengaruh kinerja keuangan konvensional; Return on Asset (ROA), Return on Equity (ROE), Residual Income (RI), dan kinerja keuangan yang lebih modern; Economic Value Added (EVA) terhadap return saham pada perusahaan ...
Bambang Sudiyatno, Toto Suharmanto
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The Impact of Macroeconomic News on Chinese Futures
International Journal of Financial Studies, 2019 Inspired by the GARCH-MIDAS model, we revisit the relationship between Chinese futures and macroeconomic factors. We introduce the level of the macroeconomic variables into the GARCH-MIDAS model in order to test the impact of the macroeconomic level on ...
Ruobing Liu +2 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source