Results 101 to 110 of about 121,135 (301)

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

Animal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao, Ming Zhong, Wenjiang Zheng, Zhendong Guo, Ye Zhou, Qiuhong Li, Lijuan Qiu, Liangwen Yu, Haishan Long, Geng Li   +9 more
wiley   +1 more source

Excess cerebral oxygen delivery follows return of spontaneous circulation in near-term asphyxiated lambs

Scientific Reports, 2020
Hypoxic-ischaemia renders the neonatal brain susceptible to early secondary injury from oxidative stress and impaired autoregulation. We aimed to describe cerebral oxygen kinetics and haemodynamics immediately following return of spontaneous circulation (
S. Badurdeen, A. Gill, M. Kluckow, C. Roberts, R. Galinsky, Sarah Klink, Suzanne L. Miller, P. Davis, G. Schmölzer, S. Hooper, G. Polglase   +10 more
semanticscholar   +1 more source

Characterization of di‐gital, tri‐gital, and tetra‐gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness

Animal Models and Experimental Medicine, EarlyView.
The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak, Lenka Tomasova, Marian Grman, Karol Ondrias   +3 more
wiley   +1 more source

The Role of Cardiac Arrest Sonographic Exam (CASE) in Predicting the Outcome of Cardiopulmonary Resuscitation; a Cross-sectional Study

Archives of Academic Emergency Medicine, 2021
Introduction: Ultrasonography (US) has been suggested as an integral part of resuscitation to identify potentially reversible causes of cardiac arrest (CA).
Babak Masoumi, Farhad Heydari, Majid Zamani, Reza Azizkhani, Mehdi Nasr Isfahani   +4 more
doaj  

Continuous monitoring of brain perfusion by cerebral oximetry after spontaneous return of circulation in cardiac arrest: a case report [PDF]

, 2022
Heng Zhou, Caiwei Lin, Jiawei Liu, Xudong Wang   +3 more
openalex   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Detection of impaired cerebral autoregulation improves by increasing arterial blood pressure variability

, 2012
Although the assessment of dynamic cerebral autoregulation (CA) based on measurements of spontaneous fluctuations in arterial blood pressure (ABP) and cerebral blood flow (CBF) is a convenient and much used method, there remains uncertainty about its ...
Allen, Robert, Birch, Anthony A., Bush, Glen, Fan, Lingke, Katsogridakis, Emmanuel, Panerai, Ronney B., Potter, John F., Simpson, David M.   +7 more
core   +1 more source

Investigation of biomarker variations post-return of spontaneous circulation following an out-of-hospital cardiac arrest

Romanian Journal of Laboratory Medicine, 2017
Objective: The objective of this research was to describe evolution of several biomarkers post-return of spontaneous circulation (ROSC) following an out-of-hospital cardiac arrest (OHCA).
Golea Adela, Rusu Adriana, Dumulesc Christiana, Bala Cornelia   +3 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source