Results 51 to 60 of about 559,150 (218)

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Climatic Challenges in the Growth Cycle of Winter Wheat in the Huang-Huai-Hai Plain: New Perspectives on High-Temperature–Drought and Low-Temperature–Drought Compound Events

Atmosphere
Global climate change increasingly impacts agroecosystems, particularly through high-temperature–drought and low-temperature–drought compound events. This study uses ground meteorological and remote sensing data and employs geostatistics, random forest ...
Geng Chen, Ke Li, Haoting Gu, Yuexuan Cheng, Dan Xue, Hong Jia, Zhengyu Du, Zhongliang Li   +7 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Development of a General Protocol to Enhance the Hydrological Analysis Techniques for Urban Catchments in Ireland

Geosciences, 2018
The hydrological analysis of urban catchments is a critical consideration for all major civil engineering projects. The purpose of this article is to develop a general protocol to enhance the established techniques for estimating runoff from Irish urban ...
Elisa Longo, John Paul Rooney
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Quantitative Vulnerability Assessment of Buildings Exposed to Landslides Under Extreme Rainfall Scenarios

Buildings
Landslides triggered by extreme rainfall often cause severe casualties and property losses. Therefore, it is essential to accurately assess and predict building vulnerability under landslide scenarios for effective risk mitigation.
Guangming Li, Dong Liu, Mengjiao Ruan, Yuhua Zhang, Jun He, Zizheng Guo, Haojie Wang, Mengchen Cheng   +7 more
doaj   +1 more source

Copula-Based Bivariate Flood Risk Assessment on Tarbela Dam, Pakistan

Hydrology, 2019
Flooding from the Indus river and its tributaries has regularly influenced the region of Pakistan. Therefore, in order to limit the misfortune brought about by these inevitable happenings, it requires taking measures to estimate the occurrence and ...
Saba Naz, Muhammad Ahsanuddin, Syed Inayatullah, Tanveer Ahmed Siddiqi, Muhammad Imtiaz   +4 more
doaj   +1 more source

Return Period Evaluation of the Largest Possible Earthquake Magnitudes in Mainland China Based on Extreme Value Theory. [PDF]

Sensors (Basel), 2021
Ma N, Bai Y, Meng S.
europepmc   +1 more source