Results 191 to 200 of about 1,551,396 (296)

Enhancing quality of mental health service for veterans with seizures

open access: yesEpilepsia, EarlyView.
Abstract Psychiatric disorders are commonly identified in people with seizures (PWS). Comorbid mood, anxiety, and trauma‐ and stressor‐related disorders are highly prevalent and not consistently recognized or treated promptly. Veterans with seizures are particularly vulnerable to neuropsychiatric comorbidities, including a higher prevalence of ...
Maria Raquel Lopez   +6 more
wiley   +1 more source

Hidden effects of dobutamine on cardiac output. [PDF]

open access: yesIntensive Care Med Exp
Lai C, Shaikhain T, Magder S.
europepmc   +1 more source

Early treatment prevents neuronal loss in experimental status epilepticus: A magnetic resonance spectroscopic imaging study

open access: yesEpilepsia, EarlyView.
Abstract Objective In status epilepticus there are concerns that the prolonged high‐intensity electrographic seizure activity causes neuronal death and poorer outcomes. In animal models of status epilepticus, early treatment that stops the seizures prevents the later development of epilepsy.
Yue Chen   +2 more
wiley   +1 more source

Incidence and impact of respiratory tract infections on outcomes in patients with status epilepticus: A 20‐year longitudinal observation

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to identify the incidence of respiratory tract infections (RTIs) in a large cohort of adult patients with status epilepticus (SE) and to characterize their associations with clinical features and outcome determinants.
Sebastian Berger   +8 more
wiley   +1 more source

Functional profiling of STXBP1 missense variants using a novel dual‐readout fluorometric assay

open access: yesEpilepsia, EarlyView.
Abstract Objective STXBP1‐related disorders (STXBP1‐RD) are among the most common genetic neurodevelopmental disorders, marked by early onset epilepsy, global developmental delay, and motor impairments. Many missense variants remain uncharacterized, limiting accurate variant interpretation and hindering development of precision therapies.
Elisa A. Waxman   +11 more
wiley   +1 more source

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

open access: yesEpilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez   +11 more
wiley   +1 more source

CYP2C19 Genotyping to Guide Clopidogrel Prescribing for Neurovascular Indications: A Survey of Institutional Approaches. [PDF]

open access: yesClin Pharmacol Ther
Stone RM   +11 more
europepmc   +1 more source

Prognosis of acute symptomatic seizures and impact of prolonged treatment with anti‐seizure medication

open access: yesEpilepsia, EarlyView.
Abstract Objectives Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti‐seizure medication (ASM) or early discontinuation, yet ASM treatment is often continued beyond hospital discharge.
Hannah Traben   +23 more
wiley   +1 more source

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