Results 21 to 30 of about 2,947,895 (397)

Milnacipran Inhibits Itch-Related Responses in Mice Through the Enhancement of Noradrenergic Transmission in the Spinal Cord

open access: yesJournal of Pharmacological Sciences, 2013
We investigated whether milnacipran, a serotonin–noradrenaline reuptake inhibitor, exhibits an antipruritic effect through the spinal action in mice.
Tsugunobu Andoh   +2 more
doaj   +1 more source

Serotonin and motherhood: From molecules to mood [PDF]

open access: yes, 2019
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming   +2 more
core   +3 more sources

Antidepressants in pregnancy and breastfeeding [PDF]

open access: yes, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Sved-Williams, A.
core   +1 more source

Different behavioral effects of maprotiline and fluxilan in rats [PDF]

open access: yesArchives of Biological Sciences, 2008
Serotonin and noradrenaline are involved in the mechanisms of action of most antidepressant drugs. We examined the effects of chronic treatment with maprotiline, a selective inhibitor of noradrenaline reuptake, and fluxilan, a selective inhibitor of ...
Spasojević Nataša   +2 more
doaj   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

Selective serotonin reuptake inhibitor and selective serotonin and norepinephrine reuptake inhibitor use and risk of fractures in adults: A systematic review and meta‐analysis

open access: yesInternational Journal of Geriatric Psychiatry, 2018
To evaluate the association between selective serotonin reuptake inhibitor (SSRI) and selective serotonin and norepinephrine reuptake inhibitor (SNRI) use and risk of fractures in older adults.
V. Khanassov   +3 more
semanticscholar   +1 more source

cAMP Signaling in Brain is Decreased in Unmedicated Depressed Patients and Increased by Treatment with a Selective Serotonin Reuptake Inhibitor

open access: yesMolecular Psychiatry, 2016
Basic studies exploring the importance of the cyclic adenosine monophosphate (cAMP) cascade in major depressive disorder (MDD) have noted that the cAMP cascade is downregulated in MDD and upregulated by antidepressant treatment.
M. Fujita   +10 more
semanticscholar   +1 more source

Ligand-based virtual screening using binary kernel discrimination [PDF]

open access: yes, 2005
This paper discusses the use of a machine-learning technique called binary kernel discrimination (BKD) for virtual screening in drug- and pesticide-discovery programmes.
Beining Chen   +14 more
core   +1 more source

The Effects of Drugs on Behavior Maintained by Social Contact: Role of Monoamines in Social Reinforcement

open access: yesFrontiers in Behavioral Neuroscience, 2022
Drug use is highly concordant among members of adolescent and young adult peer groups. One potential explanation for this observation is that drugs may increase the reinforcing effects of social contact, leading to greater motivation to establish and ...
Jessica L. Sharp, Mark A. Smith
doaj   +1 more source

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

open access: yes, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P   +8 more
core   +1 more source

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