To explore the prescribing patterns of selective serotonin reuptake inhibitors (SSRIs) before, during and after pregnancy in six European population‐based databases.
Rachel A. Charlton +14 more
semanticscholar +1 more source
Oromandibular dystonia associated with sertraline in an adolescent patient
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed to treat a variety of psychiatric disorders. Sertraline is a relatively selective serotonin reuptake inhibitor with some dopamine reuptake inhibitor activity.
Sevcan Sarısoy +2 more
doaj +1 more source
Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus. [PDF]
The relationships among hippocampal neurogenesis, depression and the mechanism of action of antidepressant drugs have generated a considerable amount of controversy.
Robert N Pechnick +6 more
doaj +1 more source
Effect of a Novel Antidepressant and Anticancer Nuc01 on Depression in Cancer Survivors
Depression in cancer survivors is commonly treated with serotonin and norepinephrine reuptake inhibitors (SNRIs), such as venlafaxine. These drugs alleviate depressive symptoms by inhibiting the reuptake of serotonin and norepinephrine.
Changchun Yuan +5 more
doaj +1 more source
Secondary Sources of Negative Symptoms in Those Meeting Criteria for a Clinical High-Risk Syndrome
Background: Negative symptoms are diagnostic characteristics of schizophrenia. They can result from primary (i.e., idiopathic) or secondary (i.e., due to other factors such as depression, anxiety, psychosis, disorganization, medication effects) features ...
Tina Gupta +6 more
doaj +1 more source
Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men [PDF]
We compared the effect of vortioxetine, paroxetine and placebo after three days of dosing on sleep architecture. This was a randomised, double-blind, four-way crossover, placebo-controlled, multiple-dose study in 24 healthy young men.
Areberg, J +4 more
core +1 more source
This randomised, double‐blind, 12‐week study compared efficacy and tolerability of flexible‐dose treatment with vortioxetine (10–20 mg/day) versus agomelatine (25–50 mg/day) in major depressive disorder patients with inadequate response to selective ...
S. Montgomery +3 more
semanticscholar +1 more source
Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Andrews, Elizabeth +5 more
core +2 more sources
First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are
J. Coplan +3 more
semanticscholar +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source

