Results 61 to 70 of about 89,927 (348)

H2O2‐Activated Serotonin Precursor Probe for Mapping Neuronal Redox Homeostasis Reveals 5‐HT Interactions with Neighboring Proteins Under Oxidative Stress

Advanced Science, EarlyView.
HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu, Jiwen Yuan, Tuanjie Zhang, Xinyi Cai, Meng Xu, Xueao Wang, Rui Wang, Bing Zhang, Hai‐Liang Zhu, Yong Qian   +9 more
wiley   +1 more source

Fluvoxamine-induced reversible euprolactinemic galactorrhea in a case of obsessive-compulsive disorder

Annals of Indian Psychiatry, 2017
Fluvoxamine is one of the commonly used selective serotonin reuptake inhibitors (SSRIs) as a first-line treatment for obsessive-compulsive disorder (OCD).
Chetan Dilip Vispute, Shubhangi R Parkar, Deepika A Singh   +2 more
doaj   +1 more source

Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool [PDF]

, 2016
Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP).
Boussery, Koen, Mattelin, Kristof, Mehuys, Els, PATTYN, EVA, Petrovic, Mirko, Somers, Annemie, Tommelein, Eline, Van Damme, Charlotte   +7 more
core   +1 more source

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

Advanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, Shengkai Gong, Yang Zhou, Feng Ding, Lu Yu, Haotian Luo, Yao Liu, Fuyang Zhang, Hui Yu, Siying Liu, Xueming Liu, Fulan Wei, Shiyu Liu   +21 more
wiley   +1 more source

Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis? [PDF]

, 2015
Background: Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown. Methods: Case report and literature review.
Treichel, Markus, Schwendener Scholl, Katharina, Kessler, Ulf, Joeris, Alexander, Nelle, Mathias   +4 more
core   +3 more sources

Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation [PDF]

, 2008
Background:The present experiment examined the responses of peripheral modulators and indices of brain serotonin (5-HT) and dopamine (DA) function and their association with perception of effort during prolonged exercise in the heat after creatine (Cr ...
Hadjicharalambous, M., Kilduff, L., Pitsiladis, Y.P.   +2 more
core   +3 more sources

A Redox‐Active and Electroactive Hydrogel Enabled by an Integrated PEDOT@PMOF Nanofiller for Post‐Infarct Myocardial Repair

Advanced Science, EarlyView.
An integrated nanoparticle PEDOT@PMOF is constructed as a redox‐active nanozyme and electroactive nanofiller in a cell‐affinity hydrogel platform for acute MI treatment. It is demonstrated that MOF‐based nanozymes have good catalytic ability, and the incorporation of PEDOT increases the conductivity.
Shuyi He, Linyu Long, Wenqi Liu, Zhicun Wang, Xiaofeng Wu, Li Yang, Yunbing Wang   +6 more
wiley   +1 more source

The role of new antidepressants in clinical practice in Canada: a brief review of vortioxetine, levomilnacipran ER, and vilazodone

Neuropsychiatric Disease and Treatment, 2017
Roger S McIntyre1,2 1Department of Psychiatry, University of Toronto, 2Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada Abstract: Although many branded and generic antidepressants are approved for the treatment of ...
McIntyre RS
doaj  

Nonstimulant Therapy for ADHD

Pediatric Neurology Briefs, 2002
The results of a multicenter, open-label, dose-titration study of GW320659, a novel norepinephrine and dopamine reuptake inhibitor, are reported from GlaxoSmithKline, Research Triangle Park, NC.
J Gordon Millichap
doaj   +1 more source

A Novel Biotinylated Homotryptamine Derivative for Quantum Dot Imaging of Serotonin Transporter in Live Cells

Frontiers in Cellular Neuroscience, 2021
The serotonin transporter (SERT) is the primary target for selective serotonin reuptake inhibitor (SSRI) antidepressants that are thought to exert their therapeutic effects by increasing the synaptic concentration of serotonin.
Ian D. Tomlinson, Oleg Kovtun, Ruben Torres, Ruben Torres, Laurel G. Bellocchio, Travis Josephs, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal   +11 more
doaj   +1 more source