Results 51 to 60 of about 6,393,826 (325)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Certificados de los mejores posters

REV SEN
1.º puesto: epidemiologia renal Gustavo Aroca Martínez, et al. Estudio: Enfermedad renal crónica en poblaciones vulnerables, afrodescendientes, indígenas y agrícolas en América Latina.
REV SEN Editores
doaj   +1 more source

Comment on ``Dispersion-Independent High-Visibility Quantum Interference ... "

, 2000
We show in this Comment that the interpretation of experimental data as well as the theory presented in Atat\"ure et al. [Phys. Rev. Lett. 84, 618 (2000)] are incorrect and discuss why such a scheme cannot be used to "recover" high-visibility quantum ...
A. V. Burlakov, M. Atatüre, M. H. Rubin, Morton H. Rubin, Sergei P. Kulik, Y.-H. Kim, Yanhua Shih, Yoon-Ho Kim   +7 more
core   +1 more source

Front Matter [PDF]

, 2014
Front ...
Econ. Rev., Turk.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

MORTALIDAD MATERNA EN EL INSTITUTO NACIONAL MATERNO PERINATAL

Revista Peruana de Investigación Materno Perinatal
MORTALIDAD ...
Enrique Guevara Río
doaj   +1 more source

Comment on 'Stability of the semiclassical Einstein equation'

, 2001
Some mathematical errors of the paper commented upon [W.-M. Suen, Phys. Rev. D 40, (1989) 315] are corrected.Comment: 3 pages, LaTeX, reprinted from Phys. Rev.
G. T. Horowitz, Hans-Jürgen Schmidt, J. Simon, V. Müller, W. M. Suen, W. M. Suen   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island

Veterinary Medicine International, 2016
The aims of this study were to evaluate the prevalence of Dog Erythrocyte Antigens (DEA) 1, 4, and 7 in Ibizan hounds, to compare the results with the prevalence of DEA in Spanish greyhounds, and to determine the risk of sensitization following the first
Eva Spada, Daniela Proverbio, Luis Miguel Viñals Flórez, Blanca Serra Gómez de la Serna, Maria del Rosario Perlado Chamizo, Luciana Baggiani, Roberta Perego   +6 more
doaj   +1 more source

Half-lives of $\alpha$-emitters approaching the N=Z line

, 2006
The half-lives of newly observed $\alpha$-emitters $^{105}$Te and $^{109}$Xe [Seweryniak \textit{et al.}, Phys. Rev. C \textbf{73}, 061301(R) (2006); Liddick \textit{et al.}, Phys. Rev. Lett.
Ren, Zhongzhou, Xu, Chang
core   +1 more source