Results 81 to 90 of about 6,393,826 (325)

Reply to the Comment on `Glassy Transition in a Disordered Model for the RNA Secondary Structure'

, 2000
We reply to the Comment by Hartmann (cond-mat/9908132) on our paper Phys. Rev. Lett. 84 (2000) 2026 (also cond-mat/9907125).Comment: 1 page, no figures. Accepted for publication in Phys.
A. K. Hartmann, A. K. Hartmann, A. Pagnani, A. Pagnani, D. Sherrington, F. Krzakala, F. Ricci-Tersenghi, G. Parisi, M. Mézard, M. Palassini, P. G. Higgs   +10 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Robust entanglement generation by reservoir engineering

, 2012
Following a recent proposal [C. Muschik et. al., Phys. Rev. A 83, 052312 (2011)], engineered dissipative processes have been used for the generation of stable entanglement between two macroscopic atomic ensembles at room temperature [H. Krauter et.
Cirac, J. Ignacio, Jensen, Kasper, Krauter, Hanna, Muschik, Christine A., Petersen, Jonas M., Polzik, Eugene S.   +5 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Editorial

Revista Científica, 2019
Un nuevo año ha comenzado, dejando atrás una amarga experiencia con la situación acaecida en el país, la cual ha afectado social, económica y financieramente a nuestras Instituciones, a nuestra Ilustre Universidad del Zulia (LUZ), la Facultad de Ciencias
Mario Pérez-Barrientos
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

(Re)creating a Pilgrimage: A Century of Pilgrimage Reports from Jesuit Novices in Canada (1864-1968)

International Journal of Religious Tourism and Pilgrimage, 2021
In 1864, a new type of pilgrimage was implemented in Canada: the Jesuit novitiate pilgrimage. Since the creation of the Society of Jesus (Jesuits) in 1540, a month-long pilgrimage is one experience required of new members.
Rev. Andr� Brouillette
doaj  

On the GBM event seen 0.4 sec after GW 150914

, 2016
In view of the recent report by Connaughton we analyse continuous TTE data of Fermi-GBM around the time of the gravitational wave event GW 150914. We find that after proper accounting for low count statistics, the GBM transient event at 0.4 s after GW ...
Burgess, J. M., Greiner, J., Savchenko, V., Yu, H. -F.   +3 more
core   +3 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source