Results 51 to 60 of about 6,107,402 (271)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Reply to Marinatto's comment on "Bell's theorem without inequalities and without probabilities for two observers"

, 2003
It is shown that Marinatto's claim [Phys. Rev. Lett. 90, 258901 (2003)] that the proof of "Bell's theorem without inequalities and without probabilities for two observers" [A. Cabello, Phys. Rev. Lett.
A. Cabello, Adán Cabello, L. Marinatto
core   +1 more source

Comment on "Liquids on Topologically Nanopatterned Surfaces" [PDF]

, 2007
Comment on "Liquids on Topologically Nanopatterned Surfaces" by O. Gang et al, Phys. Rev. Lett. 95, 217801 (2005). See also an erratum published by O. Gang et al (Phys Rev Lett, to appear)Comment: (1 page, 1 figure). Phys. Rev.
Rascon, C.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Presencia de aborto y mortinatos en cabras inmunizadas

Revista Mexicana de Ciencias Pecuarias, 2012
Se evaluó la presencia de abortos en cabras vacunadas contra brucelosis en zonas endémicas. Se trabajó con 243 cabras en explotaciones extensivas, 57 fueron vacunadas con RB51 a una dosis de 1 x 1010 ufc/ml, 68 cabras con rfbK a 1 x 109 ufc, 97 cabras ...
Rocío Villa, Marcell Perea, Efrén Díaz Aparicio, Alicia Soberón Mobarak, Laura Hernández Andrade, Francisco Suárez Güemes   +5 more
doaj  

Production of HIV particles is regulated by altering sub-cellular localization and dynamics of Rev induced by double-strand RNA binding protein. [PDF]

PLoS ONE, 2011
Human immunodeficiency virus (HIV)-1 encoded Rev is essential for export from the nucleus to the cytoplasm, of unspliced and singly spliced transcripts coding for structural and nonstructural viral proteins.
Silvio Urcuqui-Inchima, Claudia Patiño, Ximena Zapata, María Patricia García, José Arteaga, Christophe Chamot, Ajit Kumar, Danièle Hernandez-Verdun   +7 more
doaj   +1 more source

Retraction of "Near-Deterministic Discrimination of All Bell States with Linear Optics," Phys. Rev. Lett. 107, 080403 (2011) and Erratum Phys. Rev. Lett. 107, 219901 (2011)

, 2012
The original versions (1 and 2) of this paper paper contain a fatal error. All my attempts to patch the error have failed. As a service to the community I explain the error in some detail.Comment: The original paper (v.
A. Lita, J. Calsamiglia, M. Pavičić, Mladen Pavičić, Z.-Y. J. Ou   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: Novel insights into the regulation of Rev nuclear import

Retrovirology, 2011
Background The HIV-1 regulatory protein Rev, which is essential for viral replication, mediates the nuclear export of unspliced viral transcripts. Rev nuclear function requires active nucleocytoplasmic shuttling, and Rev nuclear import is mediated by the
Sheehy Noreen, Yeo Geok P, Jarboui Mohamed, Tsuji Takahiro, Gu Lili, Hall William W, Gautier Virginie W   +6 more
doaj   +1 more source