Results 81 to 90 of about 6,107,402 (271)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies.

open access: yesPLoS Pathogens
The HIV-1 Rev-RRE regulatory axis plays a crucial role in viral replication by facilitating the nucleo-cytoplasmic export and expression of viral mRNAs with retained introns.
Godfrey A Dzhivhuho   +6 more
doaj   +1 more source

The Jembrana disease virus Rev protein: Identification of nuclear and novel lentiviral nucleolar localization and nuclear export signals.

open access: yesPLoS ONE, 2019
The lentiviral Rev protein, which is a regulatory protein essential for virus replication, has been first studied in the human immunodeficiency virus type 1 (HIV-1). The main function of Rev is to mediate the nuclear exportation of viral RNAs. To fulfill
Claude Marchand   +2 more
doaj   +1 more source

A doxology to Christ (Rev. 1:5e-6)

open access: yesIn die Skriflig, 2006
Revelation 1:5e-6 is a doxology, an eulogy on the characteristics (attributes) of Christ. Christ’s churches celebrate the enduring love of Christ, who by a once-and-for-all historical act redeemed them from enslavement to sin. Through this redemptive
J. C. de Smidt
doaj   +1 more source

Comment on "Spin Dynamics of the 2D Spin 1/2 Quantum Antiferromagnet Copper Deuteroformate Tetradeuterate (CFTD)"

open access: yes, 2002
Comment on "Spin Dynamics of the 2D Spin 1/2 Quantum Antiferromagnet Copper Deuteroformate Tetradeuterate (CFTD)", H. M. Ronnow et al., Phys. Rev. Lett. 87, 037202 (2001)Comment: 1 page, 1 figure, REVTeX, to be published in Phys.
Ivan Spremo, Peter Kopietz, S. Tyč
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Assessment on reticuloendotheliosis virus infection in specific-pathogen-free chickens based on detection of yolk antibody.

open access: yesPLoS ONE, 2019
Reticuloendotheliosis virus (REV) is the most frequent exogenous virus that contaminates attenuated vaccines. Therefore, it is extremely important to select REV-free specific-pathogen-free (SPF) chicken embryos.
Yang Li   +10 more
doaj   +1 more source

Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Angiotensin II (Ang II) regulates the expression of some core clock genes; excess Ang II leads to atherosclerosis advancement.
Shipeng Wang   +7 more
doaj   +1 more source

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