Results 131 to 140 of about 147,250 (310)

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao, Jean G. Malavé, Joseph S. Rossi, Francesco Franchi, Ellen C. Keeley, Dominick J. Angiolillo, George A. Stouffer, Larisa H. Cavallari, Craig R. Lee   +8 more
wiley   +1 more source

A non-interventional cardiologist’s guide to coronary chronic total occlusions

Frontiers in Cardiovascular Medicine
Coronary chronic total occlusions (CTO) are present in up to one-third of patients with coronary artery disease (CAD). It is thus essential for all clinical cardiologists to possess a basic awareness and understanding of CTOs, including optimal ...
Lindsey Cilia, Lindsey Cilia, Michael Megaly, Rhian Davies, Behnam N. Tehrani, Wayne B. Batchelor, Alexander G. Truesdell, Alexander G. Truesdell   +7 more
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Sex Differences in Computed Tomography Coronary Stenosis Severity Versus Flow Impairment and Impact on Revascularization, Clinical Events and Health Care Costs: A FORECAST Substudy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The impact of sex‐related differences in coronary atheroma and flow impairment severity on clinical events and costs remains unclear. Methods and Results This is a secondary analysis of patients with stable coronary artery disease who ...
Lavinia Gabara, Jonathan Hinton, Mohamed Kira, James Shambrook, Ausami Abbas, Sam Wilding, Jonathon A. Leipsic, Pamela S. Douglas, Nick Curzen   +8 more
doaj   +1 more source

The influence of polymorbidity, revascularization, and wound therapy on the healing of arterial ulceration

, 2008
Joerg Tautenhahn1, Ralf Lobmann2, Brigitte Koenig3, Zuhir Halloul1, Hans Lippert1, Thomas Buerger11Department of General, Visceral and Vascular Surgery; 2Department of Endocrinology and Metabolism; 3Institute for Medical Microbiology, Medical School ...
Zuhir Halloul, Ralf Lobmann, Brigitte Koenig, Joerg Tautenhahn, Hans Lippert, Thomas Buerger   +5 more
core  

Angioplasty, bypass surgery or medical treatment: how should we decide? [PDF]

, 2002
Coronary revascularisation continues to be underused despite evidence that this results in poorer ...
Denvir, MA, Denvir, M.A., Pell, J.P., Pell, J   +3 more
core  

Endovascular Revascularization of Below-the-Knee Arteries: Prospective Short-Term Angiographic and Clinical Follow-up

, 2011
PURPOSE: To evaluate arterial lesion characteristics and their impact on angiographic and clinical outcomes after endovascular below-the-knee (BTK) revascularization.
Keo, Hak-Hong, Diehm, Nicolas, Hak-Hong Keo, Iris Baumgartner, Willenberg, Torsten, Do, Dai-Do, Torsten Willenberg, Baumgartner, Iris, Baumann, Frederic, Dai-Do Do, Nicolas Diehm, Frederic Baumann   +11 more
core   +1 more source

The in‐hospital administration of sacubitril/valsartan in acute myocardial infarction: A meta‐analysis

ESC Heart Failure, Volume 12, Issue 2, Page 998-1012, April 2025.
In patients with Acute Myocardial Infarction related heart failure, the in‐hospital administration of ARNIs was associated with a reduced risk of MACEs and re‐hospitalizations for heart failure, as well as cardiac remodeling, compared to standard therapy.
Gianluca Di Pietro, Riccardo Improta, Paolo Severino, Andrea D'Amato, Lucia Ilaria Birtolo, Ovidio De Filippo, Antonio Lattanzio, Raffaele De Cristofaro, Giacchino Galardo, Fabrizio D'Ascenzo, Roberto Badagliacca, Gennaro Sardella, Maurizio Volterrani, Francesco Fedele, Carmine Dario Vizza, Massimo Mancone   +15 more
wiley   +1 more source

Assessment of indications in interventional cardiology: appropriateness and necessity of coronary angiography and revascularization

, 2003
In this study we present appropriateness and necessity assessments of coronary angiographies and revascularizations to determine adherence to Swiss guidelines by using the computerized second-opinion system (SOS) as a reference. We prospectively compared
Kapetanios, E, Gerstl, P., Lee, C.Y., Bertel, O., Bertel, O, Gerstl, P, Schilling, J, Schilling, J., Kapetanios, E., Lee, C Y   +9 more
core   +1 more source