Results 141 to 150 of about 147,250 (310)
Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial
ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.Abstract Aims
The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of
the EXCELLENT Trial Investigators +17 morewiley +1 more sourceWhat constitutes optimal surgical revascularization? Answers from the bypass angioplasty revascularization investigation (BARI)
, 2002 ObjectivesThe study was done to derive the optimum definition of complete revascularization in coronary artery bypass surgery.Background“Complete revascularization” has been considered the goal of coronary artery bypass operations, but various ...Jones, Robert H, Richard J Shemin, Detre, Katherine M, Schaff, Hartzell V, Hartzell V Schaff, Shemin, Richard J, Robert H Jones, Gabriel S Aldea, Thomas J Vander Salm, Aldea, Gabriel S, Katherine M Detre, Kevin E Kip, Vander Salm, Thomas J, Kip, Kevin E +13 morecore +1 more sourceeGFR slope as predictor of mortality in heart failure patients
ESC Heart Failure, Volume 12, Issue 2, Page 1217-1226, April 2025.Abstract Aims
Heart failure (HF) leads to an imbalance between heart and kidney function, resulting in poor outcomes. However, the prognostic significance of the estimated glomerular filtration rate (eGFR) trajectory in HF patients remains unclear. We analysed electronic health records (EHRs) of real‐world HF patients, assessing eGFR trajectories and ...Sofie Verstreken, Monika Beles, Clara L. Oeste, Ana Moya, Imke Masuy, Riet Dierckx, Ward Heggermont, Jeroen Dauw, Dries Hens, Jozef Bartunek, Marc Vanderheyden +10 morewiley +1 more sourceMultivessel versus culprit lesion only percutaneous revascularization plus potential staged revascularization in patients with acute myocardial infarction complicated by cardiogenic shock: design and rationale of CULPRIT-SHOCK trial
, 2016 Background
In acute myocardial infarction complicated by cardiogenic shock (CS), up to 80% of patients present with multivessel coronary artery disease. Currently, the best revascularization strategy is unknown.Windecker, Stephan, Meyer-Saraei, Roza, Thiery, Joachim, Desch, Steffen, Huber, Kurt, Fuernau, Georg, Ceglarek, Uta, Piek, Jan J, Briggs, Andrew, Piek, Jan J., Serpytis, Pranas, Stepinska, Janina, Vrints, Christiaan, Zeymer, Uwe, de Waha, Suzanne, Noc, Marko, Schneider, Steffen, Savonitto, Stefano, Thiele, Holger, Oldroyd, Keith, Montalescot, Gilles, Schuler, Gerhard, Torremante, Patrizia +22 morecore +1 more sourceAssociation of BMI with adherence and outcome in heart failure patients treated with wearable cardioverter defibrillator
ESC Heart Failure, Volume 12, Issue 2, Page 1295-1303, April 2025.Abstract Background
Obesity is a known risk factor for cardiovascular disease (CVD), yet an ‘obesity paradox’ has been observed in various CVD contexts. The impact of obesity on heart failure (HF) patients treated with a wearable cardioverter‐defibrillator (WCD) remains underexplored.Mohammad Abumayyaleh, Katharina Koepsel, Julia W. Erath, Thomas Kuntz, Norbert Klein, Boldizsar Kovacs, Firat Duru, Ardan M. Saguner, Christian Blockhaus, Dong‐In Shin, Fabienne Kreimer, Michael Gotzmann, Hendrik Lapp, Thomas Beiert, Assem Aweimer, Andreas Mügge, Christel Weiß, Ibrahim El‐Battrawy, Ibrahim Akin +18 morewiley +1 more sourceSacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats
ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims
Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen +16 morewiley +1 more sourceCardiogenic shock mortality according to Aetiology in a Mediterranean cohort: Results from the Shock‐CAT study
ESC Heart Failure, Volume 12, Issue 2, Page 1336-1345, April 2025.Abstract Aims
Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.Cosme García‐García, Teresa López‐Sobrino, Esther Sanz‐Girgas, Maria R. Cueto, Jaime Aboal, Pablo Pastor, Irene Buera, Alessandro Sionis, Rut Andrea, Judit Rodríguez‐López, Jose Carlos Sánchez‐Salado, Carlos Tomas, Jordi Bañeras, Albert Ariza, Josep Lupón, Antoni Bayés‐Genís, Ferran Rueda, Grup de Treball de Cures Agudes Cardiològiques Societat Catalana de Cardiologia +17 morewiley +1 more sourceCardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?
ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo +10 morewiley +1 more sourceBioactive Magnesium Silicate Activating Myocardial Energy Metabolism For Infarcted Myocardium Repair
Exploration, EarlyView.ABSTRACT
The heart is a highly energy‐dependent organ, developing bioenergy‐activating biomaterials to activate myocardial adenosine triphosphate (ATP) production and restore dysregulated energy homeostasis is a promising solution for its functional recovery.Zhibin Liao, Chen Qin, Erhong Song, Chengbin Ding, Zhixu Wang, Yan Sun, Chen Song, Junjie Liu, Jingge Ma, Hongjian Zhang, Leyu Wang, Chengtie Wu +11 morewiley +1 more source