Results 81 to 90 of about 235,394 (339)

Gamma Irradiation of Poly(lactide‐co‐glycolide) Scaffolds Reduces the Mechanical Stability and Function of Islet Grafts in Diabetic Nonhuman Primates

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Clinical islet transplantation has long been investigated as a potential cure for type 1 diabetes (T1D), yet standard intrahepatic delivery leaves islets prone to an instant blood‐mediated inflammatory response. Herein, we investigated the design of microporous poly(D,l‐lactide‐co‐glycolide) (PLG) scaffolds for extrahepatic islet ...
Jessica L. King, Christopher Spencer, Richard Youngblood, Kelly Crumley, Elizabeth Bealer, Peter D. Rios, Ira Joshi, Sofia Ghani, Douglas Isa, James J. McGarrigle, David Cook, Conor Locke, Adam Abraham, Andrea Clark, José Oberholzer, Lonnie D. Shea   +15 more
wiley   +1 more source

Intraoperative graft patency validation: Friend or foe?Central Message

JTCVS Techniques, 2021
Rami Akhrass, MD, Faisal G. Bakaeen, MD
doaj   +1 more source

Endothelial Mechanotransduction, Redox Signaling and the Regulation of Vascular Inflammatory Pathways

Frontiers in Physiology, 2018
The endothelium that lines the interior of blood vessels is directly exposed to blood flow. The shear stress arising from blood flow is “sensed” by the endothelium and is “transduced” into biochemical signals that eventually control vascular tone and ...
Shampa Chatterjee
doaj   +1 more source

The optimal treatment of multivessel coronary artery disease [PDF]

, 2014
The practice of percutaneous coronary intervention has overtaken coronary bypass surgery in the treatment of ischaemic heart disease. Several randomized controlled as well as registry and observational trials have addressed the issue of patient selection
Manche, Alexander
core  

Coronary-artery bypass surgery in patients with ischemic cardiomyopathy [PDF]

, 2016
BACKGROUND The survival benefit of a strategy of coronary-artery bypass grafting (CABG) added to guideline-directed medical therapy, as compared with medical therapy alone, in patients with coronary artery disease, heart failure, and severe left ...
Cox DR, Eric J. Velazquez, George Sopko, Hussein R. Al-Khalidi, Jae K. Oh, James A. Hill, Jean L. Rouleau, Julio A. Panza, Kerry L. Lee, Lilin She, Mark C. Petrie, Muhlbaier LH, Patrice Desvigne-Nickens, Qiu P, Robert E. Michler, Robert H. Jones, Robert O. Bonow, Topkara VK, Torsten Doenst, Vanessa L. Moore   +19 more
core   +1 more source

Silence of the limbs: pharmacological symptomatic treatment of intermittent claudication [PDF]

, 2010
Several oral "vasoactive" drugs claim to increase walking capacity in patients with intermittent claudication (IC). Naftidrofuryl, cilostazol, buflomedil, and pentoxifylline are the most studied molecules.
De Backer, Gui, De Backer, Tine, De Buyzere, Marc, Van Bortel, Lucas, Vander Stichele, Robert   +4 more
core   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Prognostic Value of Hospital Frailty Risk Score and Clinical Outcomes in Critical Limb‐Threatening Ischemia and End‐Stage Kidney Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background End‐stage kidney disease (ESKD) is commonly associated with critical limb‐threatening ischemia (CLTI) and frailty. Yet there are no specific tools to predict outcomes of CLTI in ESKD, particularly those that incorporate frailty.
Monil Majmundar, Wan‐Chi Chan, Vivek Bhat, Kunal N. Patel, Kirk A. Hance, Georges Hajj, Axel Thors, Kamal Gupta   +7 more
doaj   +1 more source

Sex Differences Persist in Time to Presentation, Revascularization, and Mortality in Myocardial Infarction Treated With Percutaneous Coronary Intervention

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Timely revascularization with percutaneous coronary intervention (PCI) reduces death following myocardial infarction. We evaluated if a sex gap in symptom‐to‐door (STD), door‐to‐balloon (DTB), and door‐to‐PCI time persists in contemporary ...
Julia Stehli, Catherine Martin, Angela Brennan, Diem T. Dinh, Jeffrey Lefkovits, Sarah Zaman   +5 more
doaj   +1 more source

Coronary artery bypass grafting (CABG) alone in moderate ischemic mitral regurgitation: is CABG really enough? [PDF]

, 2016
No abstract ...
Nappi, Francesco, Spadaccio, Cristiano
core   +1 more source