Results 151 to 160 of about 49,879 (288)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The experience of gay Christian men attending collaborative workshops facilitated by a sexual health professional and a priest. [PDF]

Sex Med
Kunelaki R, Bennett Z, Cellek S, Roder C.   +3 more
europepmc   +1 more source

Joseph Smith Papers. Manuscript Revelation Books, facsimile edition

, 2012
Robin Scott Jensen, James B. Allen, Robert J. Woodford, Steven C. Harper   +3 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Unusual Revelation of an Anomalous Right Coronary Artery: Non-ST Segment Elevation Myocardial Infarction (NSTEMI) in the Context of Drug Abuse. [PDF]

Cureus
Kadrie AA, Black S, Balguri S, Cary C.
europepmc   +1 more source

aiGeneR 1.0: An Artificial Intelligence Technique for the Revelation of Informative and Antibiotic Resistant Genes in Escherichia coli [PDF]

Debasish Swapnesh Kumar Nayak, Saswati Mahapatra, Sweta Padma Routray, Swayamprabha Sahoo, Santanu Kumar Sahoo, Mostafa M. Fouda, Narpinder Singh, Esma R. Isenović, Luca Saba, Jasjit S. Suri, Tripti Swarnkar   +10 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

AT-17 redefines local anesthetics by targeting mitochondrial apoptosis. [PDF]

Acta Pharm Sin B
Chen X.
europepmc   +1 more source

Dimensões de um modelo de gestão da informação no campo da Ciência da Informação: uma revelação da produção científica do Enancib | Dimensions of a model of information management in the field of Information Science: a revelation of scientific production

, 2011
Irma Gracielle Carvalho de Oliveira Souza, Emeide Nóbrega Duarte   +1 more
openalex   +1 more source

Translational Mini-Review Series on B cell subsets in disease. Reconstitution after haematopoietic stem cell transplantation – revelation of B cell developmental pathways and lineage phenotypes [PDF]

, 2011
Mats Bemark, Jakob Holmqvist, Jonas Abrahamsson, Karin Mellgren   +3 more
openalex   +1 more source