Results 231 to 240 of about 97,587 (315)

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

open access: yesAdvanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha   +11 more
wiley   +1 more source

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li   +13 more
wiley   +1 more source

POCUS for Detection of Esophageal and Gastric Foreign Bodies. [PDF]

open access: yesPOCUS J
Lamour D   +4 more
europepmc   +1 more source

Unveiling Dipolar Interaction‐Driven Magnetic Field Inhomogeneities in T2 MRI Contrast Agents

open access: yesAdvanced Science, EarlyView.
In this study, chemically designed nanoscale‐distance‐tuned based on silica‐coated iron oxide nanoparticles are used to investigate how dipolar interactions affect magnetic resonance imaging (MRI) contrast. By varying shell thickness, researchers modulated dipolar interactions and observed an exponential increase in transverse relaxivity (r2) that ...
Pelayo García‐Acevedo   +6 more
wiley   +1 more source

Reverberation chambers a la carte: An overview of the different mode-stirring techniques

open access: yesIEEE Electromagnetic Compatibility Magazine, 2017
Ramiro Serra   +9 more
semanticscholar   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu   +13 more
wiley   +1 more source

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