Results 11 to 20 of about 1,223,887 (345)

THE PATTERN OF PRIMOGENITURE REVERSAL AS AN EVIDENCE FOR THE UNIFIED NATURE OF GENESIS

Богословські роздуми: Східноєвропейський журнал богословʼя, 2021
The source-critical approach to biblical literature accentuated the diversity of material that constitutes ancient books of the Bible. In the past several decades, however, some scholars shifted their attention to the final canonical and literary ...
Eduard BORYSOV
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Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter

Frontiers in Oncology, 2020
The efficacy of anti-cancer drugs in patients can be attenuated by the development of multi-drug resistance (MDR) due to ATP-binding cassette (ABC) transporters overexpression.
Hai-Ling Gao, Hai-Ling Gao, Pranav Gupta, Qingbin Cui, Yunali V. Ashar, Zhuo-Xun Wu, Leli Zeng, Leli Zeng, Zi-Ning Lei, Qiu-Xu Teng, Charles R. Ashby, Yingjun Guan, Zhe-Sheng Chen   +12 more
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Lipolysis sensation by white fat afferent nerves triggers brown fat thermogenesis

Molecular Metabolism, 2016
Objective: Metabolic challenges, such as a cold environment, stimulate sympathetic neural efferent activity to white adipose tissue (WAT) to drive lipolysis, thereby increasing the availability of free fatty acids as one source of fuel for brown adipose ...
John T. Garretson, Laura A. Szymanski, Gary J. Schwartz, Bingzhong Xue, Vitaly Ryu, Timothy J. Bartness   +5 more
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Restoring Blood Pressure in Hypertensive Mice Fails to Fully Reverse Vascular Stiffness

Frontiers in Physiology, 2020
BackgroundHypertension is a well-established driver of vascular remodeling and stiffening. The goal of this study was to evaluate whether restoring normal blood pressure (BP) fully restores vascular stiffness toward that of normotensive controls ...
Jochen Steppan, Sandeep Jandu, William Savage, Huilei Wang, Sara Kang, Roshini Narayanan, Daniel Nyhan, Lakshmi Santhanam, Lakshmi Santhanam, Lakshmi Santhanam   +9 more
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Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity

eLife, 2022
Developmental trajectories of gene expression may reverse in their direction during ageing, a phenomenon previously linked to cellular identity loss. Our analysis of cerebral cortex, lung, liver, and muscle transcriptomes of 16 mice, covering development
Hamit Izgi, Dingding Han, Ulas Isildak, Shuyun Huang, Ece Kocabiyik, Philipp Khaitovich, Mehmet Somel, Handan Melike Dönertaş   +7 more
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Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala

eLife, 2016
Socially-conveyed rules and instructions strongly shape expectations and emotions. Yet most neuroscientific studies of learning consider reinforcement history alone, irrespective of knowledge acquired through other means.
Lauren Y Atlas, Bradley B Doll, Jian Li, Nathaniel D Daw, Elizabeth A Phelps   +4 more
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Controlling magnetization reversal in Co/Pt nanostructures with perpendicular anisotropy [PDF]

, 2009
We demonstrate a simple method to tailor the magnetization reversal mechanisms of Co/Pt multilayers by depositing them onto large area nanoporous anodized alumina (AAO) with various aspect ratios, A = pore depth/diameter.
Dumas, Randy K., Eibagi, Nasim, Lai, Chih-Huang, Liu, Kai, Rahman, M. Tofizur, Shams, Nazmun N, Wu, Yun-Chung   +6 more
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A Combination of Leucine, Metformin, and Sildenafil Treats Nonalcoholic Fatty Liver Disease and Steatohepatitis in Mice

International Journal of Hepatology, 2016
Sirt1, AMPK, and eNOS modulate hepatic energy metabolism and inflammation and are key players in the development of NASH. L-leucine, an allosteric Sirt1 activator, synergizes with low doses of metformin or sildenafil on the AMPK-eNOS-Sirt1 pathway to ...
Antje Bruckbauer, Jheelam Banerjee, Lizhi Fu, Fenfen Li, Qiang Cao, Xin Cui, Rui Wu, Hang Shi, Bingzhong Xue, Michael B. Zemel   +9 more
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Central angiotensin 1–7 triggers brown fat thermogenesis

Physiological Reports, 2023
We tested the hypothesis that third ventricular (3V) injections of angiotensin 1–7 (Ang 1–7) increases thermogenesis in brown adipose tissue (BAT), and whether the Mas receptor mediates this response.
F. S. Evangelista, T. J. Bartness
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Quantifying Remission Probability in Type 2 Diabetes Mellitus

Clinics and Practice, 2021
Type 2 diabetes mellitus (T2DM) is a chronic progressive disorder and is associated with significant morbidity and mortality. The concept of T2DM remission and the reversal of diabetic parameters to normal levels has been gaining momentum over the past ...
Sanjay Kalra, Ganapathi Bantwal, Nitin Kapoor, Rakesh Sahay, Saptarshi Bhattacharya, Beatrice Anne, Raju A Gopal, Sunil Kota, Ashok Kumar, Ameya Joshi, Debmalya Sanyal, Mangesh Tiwaskar, Ashok Kumar Das   +12 more
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