Results 41 to 50 of about 312,344 (268)
Reversal of Hypolipidemia in Chronic Hepatitis C Patients After Successful Antiviral Therapy
Journal of the Formosan Medical Association, 2011 Chronic infection with the hepatitis C virus (HCV) is associated with impaired lipid metabolism. The aim of this study was to determine the impact of antiviral response on the serial change of serum lipids in chronic HCV patients. Methods: A total of 165
Yuan-Hung Kuo +7 more
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From Reversible Semantics to Reversible Debugging [PDF]
, 2018 This paper presents a line of research in reversible computing for concurrent systems. This line of research started in 2004 with the definition of the first reversible extensions for concurrent process calculi such as CCS, and is currently heading to the production of practical reversible debuggers for concurrent languages such as Erlang.
openaire +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
TH Open, 2019 Idarucizumab is a humanized antigen binding fragment (Fab) of a recombinant anti-dabigatran monoclonal antibody (IgG1-kappa) that allows rapid and sustained reversal of dabigatran-induced anticoagulation in case of bleeding or urgent surgery.
Nicolas Gendron +5 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Pharmacology Research & Perspectives, 2022 Opioid‐induced respiratory depression (OIRD) is a potentially life‐threatening complication of opioid consumption. Apart from naloxone, an opioid antagonist that has various disadvantages, a possible reversal strategy is treatment of OIRD with the ...
Marieke Hyke Algera +8 more
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Reversible Computation vs. Reversibility in Petri Nets [PDF]
Science of Computer Programming, 2016 Abstract Petri nets are a general formal model of concurrent systems which supports both action-based and state-based modelling and reasoning. One of important behavioural properties investigated in the context of Petri nets has been reversibility, understood as the possibility of returning to the initial marking from any reachable net marking.
Kamila Barylska +3 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
La douleur comme « matrice » de la vie intérieure chez Nietzsche [PDF]
Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2011 This paper attempts to put some order among the different notions of pain that are to be found in the Nietzschean philosophical corpus. It tries to show that there is a mutation of the Nietzschean concept of pain, from the notion of pain as evaluation to
Ciprian Jeler
doaj