Results 91 to 100 of about 654,215 (305)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Expertise reversal effect on reading comprehension: a case of english for specific purposes (ESP)
Ho Chi Minh City Open University Journal of Science - Social Sciences, 2017 Cognitive Load Theory assists researchers in designing instructional procedures that can lead to enhancement of reading skills. This paper aims to examine cognitive load effect as expertise reversal effect on reading comprehension of English for Specific
Huynh Cong Minh Hung
doaj
CREDIT SCORE MIGRATION ANALYSIS OF FARM BUSINESSES: CONDITIONING ON BUSINESS CYCLES AND MIGRATION TRENDS [PDF]
This study examines credit score migration rates of farm businesses. We test whether migration probabilities differ across business cycles. Our results suggest that agricultural credit ratings are more likely to improve during expansions and deteriorate ...
Katchova, Ani L., Phillips, Jill
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Experimental Test of the State Estimation-Reversal Tradeoff Relation in General Quantum Measurements
Physical Review X, 2014 When a measurement has limited strength, only partial information, regarding the initial state, is extracted, and, correspondingly, there is a probability to reverse its effect on the system and retrieve the original state.
Geng Chen +14 more
doaj +1 more source
Measurement of Wave Chaotic Eigenfunctions in the Time-Reversal Symmetry-Breaking Crossover Regime
, 2000 We present experimental results on eigenfunctions of a wave chaotic system in the continuous crossover regime between time-reversal symmetric and time-reversal symmetry-broken states.
Anlage, Steven M. +6 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Evolutionary ApplicationsEctothermic vertebrates with genotypic sex determination may adjust their sexual phenotype to early‐life environmental conditions by sex reversal, and theoretical models predict diverse consequences for population dynamics and microevolution under ...
Veronika Bókony +5 more
doaj +1 more source
Null-test signal for T-invariance violation in $pd$ scattering
, 2015 The integrated proton-deuteron cross section $\widetilde\sigma$ for the case of the incident proton vector polarization $p_y^p$ and tensor polarization $P_{xz}$ of the deuteron target provides a null test signal for time-reversal invariance violating but
Temerbayev, Azamat, Uzikov, Yuriy
core +1 more source