Results 211 to 220 of about 23,572,323 (347)

A Two-Stage Allocation-Transportation Framework with Improved Holistic Swarm Optimization for Port Cargo Transportation Planning. [PDF]

Biomimetics (Basel)
Lu C, Li Y, Yang L, Liu T, Wang Y, Cai S.   +5 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Early-Stage Corticostriatal Hyperactivity Impairs Cognitive Flexibility Alongside Striatal Cholinergic Dysfunction in an Alzheimer's Disease Model. [PDF]

Nat Commun
Huang Y, Xie X, Huang Z, Chen R, Gangal H, Wang X, de Souza KA, Hunter J, Wu X, Reddy DS, Chin J, Wang J.   +11 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Peri-Interventional Prophylactic Plasma Transfusion. [PDF]

Medicina (Kaunas)
Filipescu D, Predoi CE, Balan C, Filipescu R, Guz D, Margineanu C, Robu C, Bubenek-Turconi SI, Ștefan MG.   +8 more
europepmc   +1 more source

Mecillinam – Reversion of Resistance and How to Test It [PDF]

EBioMedicine, 2017
openaire   +3 more sources

Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats

Psychopharmacology, 2008
M. D. Lapiz-Bluhm, A. Soto-Piña, J. Hensler, D. Morilak   +3 more
semanticscholar   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Time Reversal Fusion for ECG Reconstruction Before and After Adversarial Fine-Tuning. [PDF]

Bioengineering (Basel)
Liu J, Chui KT, Lee LK, Chi HR, Yip TY.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source