Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Reverse-pyramid—Steep boarding method.
Reverse-pyramid—Steep boarding method.
Anca Gabriela Molănescu (13184268) +4 more
core +1 more source
A Sustainable Reverse Engineering Process [PDF]
Reverse engineering mimics critical features of an existing object to create its accurate or enhanced virtual/physical models. It is thus useful in creating the digital footprints of an object. It requires sophisticated devices, computing facilities, and
Ullah, AMM Sharif +3 more
core +1 more source
Maneuvering Performance in the Colonial Siphonophore, Nanomia bijuga
The colonial cnidarian, Nanomia bijuga, is highly proficient at moving in three-dimensional space through forward swimming, reverse swimming and turning.
Kelly R. Sutherland +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Incorporating Reverse Engineering Methodology into Engineering Curricula [PDF]
Wanamaker, Trevor W., M.S., Purdue University, May 2012. Incorporating Reverse Engineering Methodology into Engineering Curricula. Major Professor: Craig L. Miller.
Wanamaker, Trevor, Wanamaker, Trevor W
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Reversible Computation vs. Reversibility in Petri Nets [PDF]
Abstract Petri nets are a general formal model of concurrent systems which supports both action-based and state-based modelling and reasoning. One of important behavioural properties investigated in the context of Petri nets has been reversibility, understood as the possibility of returning to the initial marking from any reachable net marking.
Kamila Barylska +3 more
openaire +3 more sources
Targeting mTOR Complex 2 in Castration-Resistant Prostate Cancer with Acquired Docetaxel Resistance
Yujie Huang,1 You Zhai,1 Meijia Wu,1 Chengdong Chang,2 Jindan Luo,3 Dongsheng Hong,1 Qingwei Zhao,1 Yao Dai,4 Jian Liu1 1Research Center for Clinical Pharmacy, Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, The First ...
Huang Y +8 more
doaj
Experimental validation of the reverse polar decomposition of depolarizing Mueller matrices [PDF]
We experimentally assess the validity of the reverse polar decomposition (R. Ossikovski et al., Opt. Lett. 32, 689 (2007)), which describes any Mueller matrix as a product of a depolarizer, a diattenuator and a retarder with the diattenuator placed after
Anastasiadou Makrina +4 more
doaj +1 more source

