Results 201 to 210 of about 113,812 (280)

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

Animal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang, Jie‐Jian Kou, Hong‐Da Zhang, Xin‐Mei Xie, Yun‐Feng Zhou, Ping Yuan, Xiao‐Bin Pang, Lu‐Ling Zhao, Jing Qiu, Yang‐Yang He   +9 more
wiley   +1 more source

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

Annals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius, Malin Säflund, Maurizio Balestrino, Manuel Cappellari, Delfina Ferrandi, Abdoreza Ghoreishi, André Peeters, Viiu‐Marika Rand, Manuela De Michele, Aleksandras Vilionskis, Andrea Zini, Niaz Ahmed   +11 more
wiley   +1 more source

Quercetin improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice fed a high-fat diet [PDF]

, 2017
Yingjie Cui, Pengbo Hou, Fahui Li, Qinghua Liu, Shucun Qin, Guanghai Zhou, Xuelian Xu, Yanhong Si, Shoudong Guo   +8 more
openalex   +1 more source

Identification of the Micro‐Ribonucleic Acid Profiles of Plant‐Derived Extracellular Vesicles and their Potential Crosskingdom Regulation

Advanced NanoBiomed Research, EarlyView.
The present study employs small RNA sequencing to identify the types and content of microRNAs (miRNAs) in four widely utilized plant‐derived extracellular vesicles (pEVs). The functional annotation reveals that the pEV miRNAs are involved in regulating the progression of human cancer and viral infection, thereby demonstrating the crosskingdom ...
Fei Wang, Junyao Deng, Shushan Mo, Jiacong Ai, Yingxian Xiao, Xiaohan Zhou, Zhenhua Li, Lanya Li   +7 more
wiley   +1 more source

Transintestinal cholesterol excretion: A secondary, nonbiliary pathway contributing to reverse cholesterol transport [PDF]

, 2017
David Q.‐H. Wang, Piero Portincasa, Patrick Tso   +2 more
openalex   +1 more source

Oxidized low-density lipoproteins and their antibodies: Relationships with the reverse cholesterol transport and carotid atherosclerosis in adults without cardiovascular diseases

, 2012
Paolla F.C. Ferreira, Vanessa Helena de Souza Zago, F. L. D’Alexandri, Natália Baratella Panzoldo, Magnus Gidlund, Rui Nakamura, Roberto Schreiber, Eliane Soler Parra, Fernanda Dutra Santiago, E.R. Nakandakare, E.C.R. Quintão, Eliana Cotta de Faria   +11 more
openalex   +1 more source

Alcohol Pattern Consumption Differently Affects the Efficiency of Macrophage Reverse Cholesterol Transport in Vivo [PDF]

, 2018
Daniela Greco, Simone Battista, Laura Mele, Antonio Piemontese, Bianca Papotti, Stefania Cavazzini, Francesco Potì, Giulia Di Rocco, Andrea Poli, Franco Bernini, Ilaria Zanotti   +10 more
openalex   +1 more source

Chemical Proteomics Reveals Human Off‐Targets of Fluoroquinolone Induced Mitochondrial Toxicity

Angewandte Chemie International Edition, EarlyView.
A schematic overview of the adverse effects of Ciprofloxacin related to mitochondrial toxicity. AIFM1 plays a role in the MIA40‐mediated import into the IMS and oxidative folding of nuclear‐encoded proteins, including ETC complexes I and IV subunits. Ciprofloxacin disrupts the IMS import machinery, impairing ETC function.
Till Reinhardt, Yassmine El Harraoui, Alex Rothemann, Adrian T. Jauch, Sigrid Müller‐Deubert, Martin F. Köllen, Timo Risch, Lianne JHC Jacobs, Rolf Müller, Franziska R. Traube, Denitsa Docheva, Stefan Zahler, Jan Riemer, Nina C. Bach, Stephan A. Sieber   +14 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe Bornscheuer   +4 more
wiley   +1 more source

Assessing the efficiency of ethyl acetate for lipid extraction as an alternative to the Folch method in selected marine low‐trophic species

Journal of the American Oil Chemists' Society, EarlyView.
The EtOAc method offers a straightforward and environmentally friendly protocol for lipid extraction, showing efficiency comparable to the Folch method, particularly in extracting lipids with high proportions of neutral lipids and free fatty acids. Abstract The recognized health benefits associated with marine omega‐3 polyunsaturated fatty acids (PUFAs)
Ying Wang, Karl‐Erik Eilertsen, Edel Oddny Elvevoll, Mari Johannessen Walquist   +3 more
wiley   +1 more source