Results 61 to 70 of about 10,576 (266)

A New ZVS Nonisolated Bidirectional DC-DC Converter with Minimal Auxiliary Element [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2013
In this paper, a new nonisolated bidirectional buck–boost dc–dc converter is introduced. The proposed converter can be operated under ZVS condition and fixed switching frequency regardless of the direction of power flow.
Nasrin Asadi Madiseh, Majid Delshad
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Hybrid switched‐capacitor‐based boost DC–DC converter with reduced voltage stress

open access: yesThe Journal of Engineering
This article presents the new hybrid switched‐capacitor (SC)‐based transformerless DC–DC converter with a high step‐up capability and common ground features.
Tan Luong Van, Thanh Hai Nguyen
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Implementation of a Parallel-Series Resonant Converter with Wide Input Voltage Range

open access: yesEnergies, 2019
A new resonant converter is presented to have the advantages of soft switching operation on power devices, without reverse recovery current loss on power diodes and wide input voltage range operation.
Bor-Ren Lin
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Pseudo-Partial-Power Switch-Multiplexed Resonant Converter with Wide Voltage Gain

open access: yesEnergies
Full-bridge resonant converters have gained widespread adoption due to their excellent performance characteristics. However, these converters face limitations in terms of gain expansion.
Xiaoying Chen   +3 more
doaj   +1 more source

A Comparative Study on the Switching Performance of GaN and Si Power Devices for Bipolar Complementary Modulated Converter Legs

open access: yesEnergies, 2019
The commercial mature gallium nitride high electron mobility transistors (GaN HEMT) technology has drawn much attention for its great potential in industrial power electronic applications.
Baochao Wang   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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