Results 41 to 50 of about 318,711 (246)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A comparison of large language models and model-driven reverse engineering for reverse engineering

open access: yesFrontiers in Computer Science
Large language models (LLMs) have been extensively researched for programming-related tasks, including program summarisation, over recent years. However, the task of abstracting formal specifications from code using LLMs has been less explored.
Hanan Siala, Kevin Lano
doaj   +1 more source

Analysis of cryptographic mechanisms used in ransomware CryptXXX v3 [PDF]

open access: yesBiuletyn Wojskowej Akademii Technicznej, 2016
The main purpose of this paper was to analysis how malicious software is using cryptographic mechanisms. Reverse engineering were applied in order to discover mechanisms used in ransomware CryptXXX v3.
Michał Glet
doaj   +1 more source

DevOps Approach Embraces Forward and Reverse Engineering

open access: yesIJAIT (International Journal of Applied Information Technology), 2021
Modern software development methods such as Agile have given customers a flexibility to provide new requirement input when development is on progress, but customers cannot access released products during development.
Acep Taryana   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Understanding Virtual Objects through Reverse Engineering

open access: yesVirtual Archaeology Review, 2012
The main objective of our research is to develop a new methodology, based on Reverse Engineering processes – 3D scan, quantitative data analysis and Artificial Intelligence techniques, in particular simulation – to study the relationship between form and
Vera Moitinho, Juan Anton Barceló
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Detecting A Botnet By Reverse Engineering

open access: yesIJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2013
— Botnet malware is a malicious program. Botnet that infects computers, called bots, will be controlled by a botmaster to do various things such as: spamming, phishing, keylogging Distributed Denial of Service (DDoS) and other activities that are ...
Oesman Hendra Kelana, Khabib Mustofa
doaj   +1 more source

Reverse engineering of the spindle assembly checkpoint. [PDF]

open access: yesPLoS ONE, 2009
The Spindle Assembly Checkpoint (SAC) is an intracellular mechanism that ensures proper chromosome segregation. By inhibiting Cdc20, a co-factor of the Anaphase Promoting Complex (APC), the checkpoint arrests the cell cycle until all chromosomes are ...
Andreas Doncic   +3 more
doaj   +1 more source

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