Results 201 to 210 of about 40,936 (256)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Trained immunity: new paradigm in the immunological memory of cardiovascular disease. [PDF]

Immunohorizons
Hope E, Gonzalez AL, Norman LS, Smith HC, Wassenaar JW, Vickers KC, Brown JD, Doran AC.   +7 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Pain Perception and Psychoemotional Responses Across Different Scaling Technologies: A Comparative Pilot Clinical Study. [PDF]

Dent J (Basel)
Turturica NC, Badea ME, Bocanet VI, Chifor R, Badea IC.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Amyloid immunotherapy for Alzheimer's disease: the case for cautious adoption. [PDF]

Arq Neuropsiquiatr
Schott JM, Marshall CR.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Development of a New Patient-Reported Outcome to Measure Fatigue in Patients with Multiple Sclerosis. [PDF]

Nurs Rep
Jorquera-Ruzzi MA, Ramo Tello C, Durà-Mata MJ, Casas I.   +3 more
europepmc   +1 more source

Development and validation of the Individual Potentials Questionnaire (IP-Q). [PDF]

Sci Rep
Sabo A, Kuan G, Abdullah S, Kuay HS, Kueh YC.   +4 more
europepmc   +1 more source

Knowledge, attitudes, and practices regarding constipation among patients with type 2 diabetes mellitus: a structural equation modeling analysis. [PDF]

Front Public Health
Wang Q, He J, Zhang D, Yu J, Tian M, Zhang Q, Zhou S, Meng M.   +7 more
europepmc   +1 more source