Results 271 to 280 of about 275,235 (344)

High expression of miR5700 in atypical type A thymoma and its role in promoting tumour progression

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
The first discovery of miR5700 in tumour progression: 1. Atypical type A thymoma was the most invasive and metastatic subtype of thymic epithelial tumour, and difficult to diagnose in pathology owing to the scarcity of specific biomarkers and well‐defined molecular targets. 2. miR‐5700 was markedly overexpressed in atypical type A thymoma. 3.
Li Zhao   +4 more
wiley   +1 more source

Loss of METTL3 m6A methyltransferase results in short‐term progression and poor treatment outcome of bladder cancer patients

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 763-774, 1 February 2026.
What's new? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala   +10 more
wiley   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 642-655, 1 February 2026.
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff   +13 more
wiley   +1 more source

Rhinovirus Infects B and CD4 T Lymphocytes in Hypertrophic Tonsils in Children

open access: yesJournal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Prolonged detection of rhinovirus (RV) in secretions after a typical cold and asymptomatic shedding are frequently reported. Although RV has been detected in human hypertrophic tonsils, its replicative status and host cell range remain unclear.
Ronaldo Martins   +14 more
wiley   +1 more source

Staphylococcus aureus Extracellular Vesicles Enhance PslE‐Mediated Pathogenesis in Pseudomonas aeruginosa

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
PslE is essential for the ability of S. aureus‐derived extracellular vesicles to enhance P. aeruginosa pathogenicity. ABSTRACT Coinfection of Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) is frequently observed. Our previous study demonstrated that S. aureus‐derived extracellular vesicles (SaEVs) promote P.
Phawinee Subsomwong   +4 more
wiley   +1 more source

Antibiotic Resistance, Biofilm Genes, and smeDEF Efflux Pump in Clinical Stenotrophomonas maltophilia Isolates From Iran

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim   +6 more
wiley   +1 more source

A novel reverse transcriptase-polymerase chain reaction based-liquid hybridisation (RT-PCR-LH) assay for early diagnosis of dengue infection

open access: hybrid, 2011
Maya B Gunesekera   +6 more
openalex   +2 more sources

Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva   +6 more
wiley   +1 more source

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