Results 91 to 100 of about 245,521 (284)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

High-Capacity Dual-Image Reversible Data Hiding in AMBTC Using Difference Expansion with Block-Wise HMAC Authentication

Applied Sciences
Reversible data hiding (RDH) is a key technique in secure multimedia applications, enabling the exact recovery of both embedded data and the original cover content.
Cheonshik Kim, Ching-Nung Yang, Lu Leng
doaj   +1 more source

Turbo Detection of Space-time Trellis-Coded Constant Bit Rate Vector-Quantised Videophone System using Reversible Variable-Length Codes, Convolutional Codes and Turbo Codes

, 2004
In this treatise we characterise the achievable performance of a proprietary video transmission system, which employs a Constant Bit Rate (CBR) video codec that is concatenated with one of three error correction codecs, namely a Reversible Variable ...
Hanzo, L., Maunder, R. G., Ng, S. X., Yeap, B. L.   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Threshold Spaces Reconfiguration: On Pinocchio’s Metamorphosis, Between Collodi and Comencini

Between, 2011
Metamorphosis is a threshold infringement marking the passage to a new configuration; an intersemiotic translation is also a threshold infringement and a code one. In the comparison between Collodi’s Le avventure di Pinocchio to Luigi Comencini’s 1972 TV
Pier Paolo Argiolas
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

An approach for automated generation of quantum computing models using deep learning

Ain Shams Engineering Journal
Quantum computing promises remarkable computational power with minimal energy consumption. However, the complexity of developing quantum circuits and codes hinders fully exploiting this potential.
Niyazi Furkan Bar, Mehmet Karakose
doaj   +1 more source

A partial encryption algorithm for medical images based on quick response code and reversible data hiding technology

BMC Medical Informatics and Decision Making, 2020
Background Medical image data, like most patient information, have a strong requirement for privacy and confidentiality. This makes transmitting medical image data, within an open network, problematic, due to the aforementioned issues, along with the ...
Jian Li, Zelin Zhang, Shengyu Li, Ryan Benton, Yulong Huang, Mohan Vamsi Kasukurthi, Dongqi Li, Jingwei Lin, Glen M. Borchert, Shaobo Tan, Gang Li, Bin Ma, Meihong Yang, Jingshan Huang   +13 more
doaj   +1 more source