Results 111 to 120 of about 246,403 (284)
Mulu Eyasu Weldekiros,1 Mulugeta Tamire,2 Adugnaw Berhane,2 Zenawi Hagos Gufue,3 Ferehiwot Hailemariam Tesfa1 1Health Education and Promotion Unit, School of Public Health, College of Health Sciences, Mekelle University, Mekelle, Ethiopia; 2Health ...
Weldekiros ME +4 more
doaj
Reverse PAC Codes: Look-Ahead List Decoding
Convolutional precoding in polarization-adjusted convolutional (PAC) codes is a recently introduced variant of polar codes. It has demonstrated an effective reduction in the number of minimum weight codewords (a.k.a error coefficient) of polar codes. This reduction has the potential to significantly improve the error correction performance.
Gu, Xinyi +2 more
openaire +2 more sources
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
A Family of Reversible BCH Codes
Cyclic codes are an interesting class of linear codes due to their efficient encoding and decoding algorithms as well as their theoretical importance. BCH codes form a subclass of cyclic codes and are very important in both theory and practice as they have good error-correcting capability and are widely used in communication systems, storage devices ...
Li, Shuxing, Ding, Cunsheng, Liu, Hao
openaire +2 more sources
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source

