Results 111 to 120 of about 86,016 (287)
Radical Ring-Closing/Ring-Opening Cascade Polymerization
, 2019 A novel strategy for the synthesis of main-chain polymers through radical ring-closing/ring-opening cascade polymerization is reported. Efficient radical cyclopolymerization was achieved through systematic optimization of the electronic properties of 1,6-
Hanchu Huang (1397098) +13 more
core +2 more sources
International Journal of Photoenergy, 2018 Photochromic 5-phenylpyrazolidin-3-one-based azomethine imines containing 2-((1H-imidazol-2-yl)methylene) 1, 2-(pyridin-2-ylmethylene) 2, 2-(quinolin-2-ylmethylene) 3, and 2-((8-hydroxyquinolin-2-yl)methylene) 4 substituents were synthesized.
Vladimir A. Bren +5 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Minimal Reversible Nonsymmetric Rings
, 2018 Marks showed that there exists a reversible non-symmetric ring of order 256 and then questioned whether or not this ring is minimal with respect to cardinality. In this work, it was shown that the cardinality of a minimal reversible non-symmetric ring is
Szabo, Steve
core
Multicolor Luminescent Supramolecular Bidirectional Shuttles Driven by Light
Advanced SciencePossessing special photophysical behavior, supramolecular space‐confined assembly is widely applied in bioimaging, information anti‐counterfeiting, and luminescent materials.
Rong Zhang +4 more
doaj +1 more source
Gynecology and Obstetrics Clinical MedicineBackground Contraceptive use after childbirth can reduce risk of unplanned pregnancy. This study estimated the prevalence of contraception use in the 1 year after childbirth.
Vanessa Perez Patel +4 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Many tubulin inhibitors are in clinical use as anti-cancer drugs. In our previous study, a novel series of 4-substituted coumarins derivatives were identified as novel tubulin inhibitors.
Wei Yan +16 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
, 2017 Through the reversible addition-fragmentation chain transfer (RAFT) copolymerization of 3-ethyl-1-vinyl-2-pyrrolidone (C2NVP) and N-vinylpyrrolidone (NVP), a series of well-defined P(C2NVP-co-NVP) copolymers were synthesized (M-n = ca. 8000 to 16,000 and
Tao Chen +8 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source