Results 101 to 110 of about 604,680 (287)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Network Communication with operators in Dedekind Finite and Stably Finite Rings [PDF]
Messages in communication networks often are considered as "discrete" taking values in some finite alphabet (e.g. a finite field). However, if we want to consider for example communication based on analogue signals, we will have to consider messages that
Riis, S
core +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Electronically tunable luminescent bis(biaryl-substituted triarylamine) ((bTAA)2) electrophores prepared via oxidative dimerization of modularly accessible arylated monomers [PDF]
Bis(biaryl-substituted triarylamines) ((bTAA)2) are readily synthesized by oxidative homocoupling from modularly accessible biaryl-substituted triarylamine (bTAA) monomers.
Regina Kohlbecher +3 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Results on Reversible Properties in Skew Monoid Rings
This paper introduces the concept of \(\sigma\)-skew strongly \(M\)-nil-reversible rings as a unified generalization of strongly \(M\)-reversible and \(M\)-compatible rings.
Eltiyeb Ali, Awn Alqahtani
core +1 more source
Combined oral contraceptives (COC) – the most popular reversible method to prevent unwanted pregnancy used in the whole world. The popularity of COC remains unchanged since the moment of their appearance [1]. Thus, in the US COC are used by each 4 out of
V. N. Prilepskaya, E. A. Minaeva
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Intra-Stromal Corneal Ring Segments
Intra-stromal corneal ring segments (ICRs) are a new modality in the treatment of corneal ectactic disorders like keratoconus, post lasik ectasia and pellucid marginal degeneration.
Ramendra Bakshi +3 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source

