Results 111 to 120 of about 582,737 (274)

The structure of balanced rings [PDF]

, 1973
Dlab V, Ringel CM. The structure of balanced rings. Proceedings of the London Mathematical Society.
Dlab, Vlastimil, Ringel, Claus Michael
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intra-Stromal Corneal Ring Segments

Delhi Journal of Ophthalmology, 2013
Intra-stromal corneal ring segments (ICRs) are a new modality in the treatment of corneal ectactic disorders like keratoconus, post lasik ectasia and pellucid marginal degeneration.
Ramendra Bakshi, Charu Khurana, Ritika Sachdev, Mahipal Sachdev   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Reverse Homoderivations on (Semi)-prime Rings

Journal of the Indonesian Mathematical Society
In this paper, we explore and examine a new class of maps known as reverse homoderivations. A reverse homoderivation refers to an additive map g defined on a ring T that satisfies the condition, g(ϑℓ)=g(ℓ)g(ϑ)+g(ℓ)ϑ+ℓg(ϑ), for all ϑ,ℓ∈T. We present various results that enhance our understanding of reverse homoderivations, including their existence in ...
Shakir Ali, Naira Noor Rafiquee, Vaishali Varshney, Outdom Dy   +3 more
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Synthesis, crystal structures and electrochemical properties of ferrocenyl imidazole derivatives

Heliyon, 2019
Six ferrocenyl imidazole derivatives substituted with -Cl, -NO2 and -CH3 on the 2-position of the 1H-imidazole ring have been synthesized. Of the six compounds, the di-substituted ferrocenes, i.e. compounds 4 (1,1′-ferrocenylmethyl(2-chloroimidazole)), 5
Ayomide H. Labulo, Bernard Omondi, Vincent O. Nyamori   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A Narrative Review on Hormonal and Reversible Contraception: Advances, Options, and Implications for Reproductive Health [PDF]

Journal of Clinical and Diagnostic Research
This narrative-based systematic review aims to examine contraception, focusing on new developments and alternative techniques. Pregnant teenagers often face challenges regarding their social standing in society.
Krushan Shah, Bhagyesh Sapkale, Rajesh Godavarthi, Kamlesh Chaudhari   +3 more
doaj   +1 more source