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Emergence of BRCA Reversion Mutations in Prostate Cancer Prior to PARP Inhibitor Exposure: Clinical and Therapeutic Implications. [PDF]
Cancer MedBackground Inactivating BRCA1/2 mutations confer sensitivity to poly(ADP‐ribose) polymerase inhibitors (PARPi) in prostate cancer (PCA). However, secondary BRCA1/2 reversion mutations (BRCArev) can restore BRCA function and mediate acquired PARPi ...
Lin DI +11 more
europepmc +2 more sources
Contesting “Conversion” and “Reversion” among Young Adult Asian American Buddhists [PDF]
Religions, 2019 This paper engages the perspectives of thirty young adult Asian American Buddhists (YAAABs) raised in non-Buddhist households. Grounded in semi-structured, one-on-one in-person and email interviews, my research reveals the family tensions and challenges ...
Chenxing Han
doaj +2 more sources
Longitudinal changes in DNA methylation during the onset of islet autoimmunity differentiate between reversion versus progression of islet autoimmunity [PDF]
Frontiers in ImmunologyBackgroundType 1 diabetes (T1D) is preceded by a heterogenous pre-clinical phase, islet autoimmunity (IA). We aimed to identify pre vs. post-IA seroconversion (SV) changes in DNAm that differed across three IA progression phenotypes, those who lose ...
Patrick M. Carry +19 more
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Vasectomy in Colombia: some remarks on its current status
Revista de la Facultad de Medicina, 2023 Sexual and reproductive rights are protected in Colombia by the 1991 Political Constitution,1 meaning that it is the State's responsibility to guarantee their fulfillment.
Alejandro Fernández-Duque
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RUDN Journal of Studies in Literature and Journalism, 2023 The study for the first time endeavours to elucidate the distinct conceptual nuances of AI-driven journalism, exploring how it reshapes the core technological and communicative attributes of the field while influencing societal dynamics.
Marina G. Shilina +3 more
doaj +1 more source
eXPRESS Polymer Letters, 2020 The vulcanization of high diene elastomers with conventional or semi-efficient vulcanization systems exhibit reversion at a higher temperature due to the breakage of the polysulfidic crosslinks established in the vulcanized network.
S. Gopi Sathi, R. Stocek, O. Kratina
doaj +1 more source
Molecules, 2016 The present study reports the reversing effects of extracts from P. americana on multidrug resistance of BEL-7402/5-FU cells, as well as a preliminary investigation on their mechanism of action.
Falu Yuan +5 more
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The Structural-Semantic Features of Computer Terms in English
Cognitive Studies | Études cognitives, 2020 The Structural-Semantic Features of Computer Terms in English The article is devoted to the study of the structural and semantic characteristics of computer terms in English.
Maryna Bogachyk, Dmytro Bihunov
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Host plant-dependent phenotypic reversion of Ralstonia solanacearum from non-pathogenic to pathogenic forms via alterations in the phcA gene [PDF]
, 2003 Ralstonia solanacearum is a plant pathogenic bacterium that undergoes a spontaneous phenotypic conversion (PC) from a wild-type pathogenic to a non-pathogenic form.
Arlat, Mathieu +6 more
core +1 more source
Metals, 2021 The martensite-to-austenite reversion mechanisms under continuous heating and annealing of metastable austenitic stainless steel subjected to cold swaging were studied.
Dmitrii Panov +7 more
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