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Results 141 to 150 of about 37,694,334 (372)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source

A brief review of atomic layer deposition: from fundamentals to applications

, 2014
Richard W. Johnson, Adam Hultqvist, Stacey F. Bent +2 more
openalex +1 more source

Reviewers, Reviewing, Reviews [PDF]

Journalism & Mass Communication Quarterly, 2021
openaire +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source

Editorial: Insights (November 2020)

Technology Innovation Management Review, 2020
Stoyan Tanev, Gregory Sandstrom
doaj +1 more source

Coping, emotion regulation, and psychopathology in childhood and adolescence: A meta-analysis and narrative review.

, 2017
Bruce E. Compas +7 more
openalex +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source

The National Economic Accounts of the United States: Review, Appraisal, and Recommendations [PDF]