Results 181 to 190 of about 26,970,723 (329)
The Beneficial and Harmful Effects of Perioperative Clonidine: Protocol for a Systematic Review With Meta-Analysis. [PDF]
Acta Anaesthesiol ScandBirkebæk S +5 more
europepmc +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Liberal Versus Restrictive Oxygenation Targets in Acute Heart Failure-A Protocol for a Systematic Review With Meta-Analysis. [PDF]
Acta Anaesthesiol ScandTaraldsen IA +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Methods for co-designing health innovations with older adults: A rapid review. [PDF]
Australas J AgeingBlouin Gagnon L +4 more
europepmc +1 more source
The Oslo Study of Untreated Syphilis Review and Commentary
, 1956 L. W. Harrison
openalex +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
PROTOCOL: Association of Antenatal Cytokine Concentrations With Neurodevelopmental Disorders of the Offspring: A Scoping Review. [PDF]
Campbell Syst RevJayasinghe IU +5 more
europepmc +1 more source