Results 51 to 60 of about 23,947,856 (359)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Shiva diagrams for composite-boson many-body effects : How they work
The purpose of this paper is to show how the diagrammatic expansion in fermion exchanges of scalar products of $N$-composite-boson (``coboson'') states can be obtained in a practical way.
Betbeder-Matibet+16 more
core +4 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Does Code Review Promote Conformance? A Study of OpenStack Patches [PDF]
Code Review plays a crucial role in software quality, by allowing reviewers to discuss and critique any new patches before they can be successfully integrated into the project code. Yet, it is unsure the extent to which coding pattern changes (i.e., repetitive code) from when a patch is first submitted and when the decision is made (i.e., during the ...
arxiv
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka+6 more
wiley +1 more source
Ranking Online Consumer Reviews [PDF]
The product reviews are posted online in the hundreds and even in the thousands for some popular products. Handling such a large volume of continuously generated online content is a challenging task for buyers, sellers, and even researchers. The purpose of this study is to rank the overwhelming number of reviews using their predicted helpfulness score.
arxiv +1 more source
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley+2 more
wiley +1 more source