Results 61 to 70 of about 27,119,175 (328)
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Bjelland Vineyards Plans Grand Opening Article [PDF]
, 1970 The grand opening of Bjelland Vineyards\u27 samples and sales building is advertised, providing information about the tasting hours and the wines that will be available. The building was made from repurposed wood and square nails from a 100-year-old barn.
The News-Review
core +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
At Bjelland Vineyards Outlook Is Exciting Article [PDF]
, 1974 This article focuses on Bjelland Vineyards and its prospects for future growth and development. Paul Bjelland is interviewed about the sales of Bjelland wines around the world, as well as some of the trials he faces as a vintner.
The News-Review
core +1 more source
Human Resources for HealthBackground Quality assessments are being introduced in many countries to improve the quality of care and maintain acceptable quality levels. In South Korea, various quality assessments are being conducted to improve the quality of care, but there is ...
Seungju Kim +3 more
doaj +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
1972 Oregon Vineyards Directory Article [PDF]
, 2015 The \u2772 Oregon Vineyards Directory (as printed in the Roseburg News-Review) features 25 vineyards larger than one acre throughout Oregon. By 1971, 138.2 acres were planted with wine grapes in Oregon, and vineyards projected significant growth for 1972
The News-Review
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Editorial: Celebrating the World of Innovation (March 2021)
Technology Innovation Management Review, 2021 Stoyan Tanev, Gregory Sandstrom
doaj +1 more source