Results 61 to 70 of about 35,471,630 (314)

Shiva diagrams for composite-boson many-body effects : How they work

open access: yes, 2007
The purpose of this paper is to show how the diagrammatic expansion in fermion exchanges of scalar products of $N$-composite-boson (``coboson'') states can be obtained in a practical way.
Betbeder-Matibet   +16 more
core   +5 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Diffusion of innovations in service organizations: systematic review and recommendations.

open access: yesMilbank Quarterly, 2004
This article summarizes an extensive literature review addressing the question, How can we spread and sustain innovations in health service delivery and organization?
T. Greenhalgh   +4 more
semanticscholar   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Overview of Bjelland Vineyards Article [PDF]

open access: yes, 1976
This article relates the origin story of Bjelland Vineyards and its available wines, including an invitation from Paul and Mary Bjelland to visit the winery and enjoy a picnic on their property.
The News-Review
core   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yes
FEBS Letters, EarlyView.
Igor Zivkovic   +2 more
wiley   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

REVIEWS [PDF]

open access: yesThe Journal of Theological Studies, 1915
n ...
openaire   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

REVIEWS [PDF]

open access: yesThe Journal of Theological Studies, 1920
n ...
openaire   +4 more sources

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