Results 61 to 70 of about 23,947,856 (359)
Factoring Expertise, Workload, and Turnover into Code Review Recommendation [PDF]
arXiv, 2023 Developer turnover is inevitable on software projects and leads to knowledge loss, a reduction in productivity, and an increase in defects. Mitigation strategies to deal with turnover tend to disrupt and increase workloads for developers. In this work, we suggest that through code review recommendation we can distribute knowledge and mitigate turnover ...
arxiv
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
Pacific Journalism Review, 2019 PINA Pacific Media Award winners at the 1995 convention.
Pacific Journalism Review
doaj +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Vaccines, 2019 Respiratory syncytial virus (RSV) causes severe lower respiratory tract disease in infants and the elderly. Although there is no licensed vaccine, RSV-F and -G glycoproteins are targets for vaccine development and therapeutics. We developed an assay that
Roberta Lynne Crim +5 more
doaj +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
PeRView: A Framework for Personalized Review Selection Using Micro-Reviews [PDF]
arXiv, 2018 In the contemporary era, social media has its influence on people in making decisions. The proliferation of online reviews with diversified and verbose content often causes problems inaccurate decision making. Since online reviews have an impact on people of all walks of life while taking decisions, choosing appropriate reviews based on the ...
arxiv