Results 91 to 100 of about 26,617,480 (363)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Facial Expression Recognition Using Computer Vision: A Systematic Review
Emotion recognition has attracted major attention in numerous fields because of its relevant applications in the contemporary world: marketing, psychology, surveillance, and entertainment are some examples.
Daniel Canedo, António J. R. Neves
doaj +1 more source
Epithelial ovarian cancer: Review article.
S. Sambasivan
semanticscholar +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Lihavuus terveyden, sairauden ja normaaliuden määrittelyn kohteena
Lihavuudesta ja lihavasta ruumiista on tullut viimeistään viime vuosikymmenen niin kutsutun lihavuusepidemiadiskurssin myötä keskeinen paitsi lääketieteellisen myös sosiaalisen ja moraalisen arvioinnin, yhteiskunnallisen keskustelun ja toimintaohjelmien ...
Hannele Harjunen
doaj
Review article: systemic treatment of hepatocellular carcinoma
The approval of the tyrosine kinase inhibitor sorafenib in 2007 marked a milestone in the treatment of hepatocellular carcinoma, as sorafenib was the first systemic therapy to show a survival benefit in patients with advanced hepatocellular carcinoma ...
M. Pinter, M. Peck‐Radosavljevic
semanticscholar +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Failed Back Surgery Syndrome: A Review Article
Postsurgical spine syndrome is becoming an increasingly common challenge for clinicians who deal with spinal disorders owing to the expanding indications for spinal surgery and the aging world population.
James R. Daniell, O. Osti
semanticscholar +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source