Results 81 to 90 of about 12,753,981 (303)

Measurement Technologies for Tribological Monitoring of Tilting‐Pad Journal Bearings: A Review

Wind Energy
Recently, there has been an uptrend in interest in adopting tilting‐pad sliding bearings for wind turbine main bearing applications. Manufacturers have opted for designs with interchangeable pads, emphasizing the importance of ease of maintenance ...
G. Nicholas, R. S. Dwyer‐Joyce
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

a-Maximization in N=1 Supersymmetric Spin(10) Gauge Theories

, 2010
A summary is reported on our previous publications about four-dimensional N=1 supersymmetric Spin(10) gauge theory with chiral superfields in the spinor and vector representations in the non-Abelian Coulomb phase.
Kawano, Teruhiko, Yagi, Futoshi
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Problems in Lattice Gauge Fixing

, 2001
We review many topics and results about numeric gauge fixing in lattice QCD.Comment: 47 pages, 16 eps figures.
Adler S. L., Adler S. L., B. TAGLIENTI, Bali G. S., Bali G. S., Batrouni G. G., Batrouni G. G., Blum T., Bock W., Bonnet F. D. R., C. PARRINELLO, Christou C., Creutz M., Cucchieri A., Davies C. T. H., DeGrand T., Del Debbio L., Del Debbio L., Di Giacomo A., Faber M., Fachin S., Fachin S., Ginsparg P. H., Girotti H. O., Giusti L., Gupta R., Hamber H. W., Hart A., Hart A., Henty D. S., Ilgenfritz E. M., L. GIUSTI, Leroy J. P., M. L. PACIELLO, Mandula J. E., Nambu Y., Parisi G., Parisi G., S. PETRARCA, Suzuki T., Vink J., Wilson K.   +41 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Sustainable Agricultural Development In Indonesia (Article Review)

, 2022
Fikriman Fikriman, Eci Prayetni, Pitriani Pitriani   +2 more
openalex   +2 more sources

Playing chicken: Theology, economics, politics and ethics in the campaign for better conditions for poultry [PDF]

, 2008
This is the author's pdf version of an article published in Epworth Review© 2008. Epworth Review © Trustees for Methodist Church Purposes.This article discusses animal welfare and Christian ethics within the context of the campaign by celebrity chefs to ...
Clough, David
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source