Results 91 to 100 of about 87,137,076 (257)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Gastroprotective effects of Zingiber officinale in rodent models of peptic ulcers: A systematic review and meta-analysis [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Peptic ulcer remains a significant global health concern, particularly in low-resource settings. Conventional treatments are often associated with side effects and recurrence, prompting interest in herbal therapies such as Zingiber officinale ...
Coana Sukmagautama +6 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2011 Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 7, 2011).; Harvested from the web on 11/8/11Official website of the Connecticut Judicial Review Council.
core +1 more source
JSES Reviews, Reports, and TechniquesManaging of rotator cuff tears, particularly those involving the subscapularis (SSC), anterosuperior cuff, and massive cuff tears with SSC insufficiency, presents significant clinical challenges.
Chang Hee Baek, MD +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The top 50 most cited articles on superior capsular reconstruction: a bibliometric analysis
JSES Reviews, Reports, and TechniquesBackground: Bibliometric analysis has been used to quantify and assess a scientific publication and its impact. The purpose of this study was to identify and review the top 50 most cited articles discussing superior capsular reconstruction (SCR). Methods:
Mallery Zeiman, BS +3 more
doaj +1 more source