Results 111 to 120 of about 29,295,499 (335)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mild Cognitive Impairment in Clinical Practice: A Review Article

open access: yesAmerican Journal of Alzheimers Disease & Other Dementias, 2018
The spectrum of cognitive decline in the elderly ranges from what can be classified as normal cognitive decline with aging to subjective cognitive impairment to mild cognitive impairment (MCI) to dementia. This article reviewed the up-to-date evidence of
Sukanya Jongsiriyanyong, P. Limpawattana
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Review Article Blastocystosis

open access: yesAL-Kindy College Medical Journal, 2019
Blastocystosis is symptomatic infection caused by the protozoal parasite Blastocystis , which resides in the intestinal tract of its hosts and it is one of the most common parasites reported in humans. It’s prevalence ranges between (30 - 50%) of the population in developing countries. This genus has a worldwide distribution and often the most commonly
openaire   +3 more sources

Nanofiltration systems and applications in wastewater treatment: Review article

open access: yesAin Shams Engineering Journal, 2018
Nanofiltration membrane (NF) is one of the most important activities employed in wastewater treatment field. It is a relatively recent development in membrane technology and it can be aqueous or non-aqueous.
M. Abdel-Fatah
semanticscholar   +1 more source

Playing chicken: Theology, economics, politics and ethics in the campaign for better conditions for poultry [PDF]

open access: yes, 2008
This is the author's pdf version of an article published in Epworth Review© 2008. Epworth Review © Trustees for Methodist Church Purposes.This article discusses animal welfare and Christian ethics within the context of the campaign by celebrity chefs to ...
Clough, David
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Measurement Technologies for Tribological Monitoring of Tilting‐Pad Journal Bearings: A Review

open access: yesWind Energy
Recently, there has been an uptrend in interest in adopting tilting‐pad sliding bearings for wind turbine main bearing applications. Manufacturers have opted for designs with interchangeable pads, emphasizing the importance of ease of maintenance ...
G. Nicholas, R. S. Dwyer‐Joyce
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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