Results 261 to 270 of about 21,282,199 (350)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Pathogenesis and Current Treatment Strategies in Rheumatoid Arthritis: A Systematic Review Article.

Ann Afr Med
Deka D.
europepmc   +1 more source

Apoptosis-inducing proteins with reduced expression in breast cancer: A review article. [PDF]

Biochem Biophys Rep
Khaleghi MM, Rouhi F, Eslami K, Shafiee F.   +3 more
europepmc   +1 more source

Review article of M. Baratin, La Naissance de la Syntaxe à Rome

, 1994
Ineke Sluiter
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article. [PDF]

Mol Med
Mehdi SF, Qureshi MH, Pervaiz S, Kumari K, Saji E, Shah M, Abdullah A, Zahoor K, Qadeer HA, Katari DK, Metz C, Mishra L, LeRoith D, Tracey K, Brownstein MJ, Roth J.   +15 more
europepmc   +1 more source

Cultural Pathology: what Ern Malley means. Review article on Michael Heyward, The Ern Malley Affair

, 1995
Philip Mead
openalex  

Reviewed article: Batista JFC, Santos MAA, Lima SO. Trend of epidemiological indicators and factors associated with tuberculosis treatment dropout and death among street people in Brazil: an ecological and cross-sectional study, 2014-2022. Epidemiol Serv Saude. 2025:34;20240273

Daniela de Almeida Pereira Duarte
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Development and prospects of natural orifice specimen extraction surgery for colorectal cancer: a review article. [PDF]

Int J Surg
Huang X, Wei R, Li Q, Qiu X, Li P, He W.
europepmc   +1 more source