Results 31 to 40 of about 5,538,712 (305)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Macular Telangiectasia Type 2: A Comprehensive Review

open access: yesClinical Ophthalmology, 2022
Kiran Chandra Kedarisetti,1 Raja Narayanan,1,2 Michael W Stewart,3 Nikitha Reddy Gurram,1 Arshad M Khanani4,5 1Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India; 2Indian Health Outcomes, Public Health and Economics ...
Kedarisetti KC   +4 more
doaj  

معیارهای تعیین‌کننده بیمارستان سبز: مرور حوزه‌ای

open access: yesمدیریت اطلاعات سلامت, 2020
مقدمه: بیمارستان سبز در جهت صرفه‌جویی منابع و انرژی، منجر به افزایش رقابت‌پذیری، بهره‌وری و کاهش هزینه‌ها می‌گردد. پژوهش حاضر با هدف شناسایی و دسته‌بندی معیارهای تعیین‌کننده بیمارستان سبز انجام شد.
Diba Norozi   +2 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Review article: The art of making mutual benefit through saving time

open access: yesInternational Journal of Information Science and Management, 2016
Review articles are considered to act as a solution for the information overload problem, especially in different scientific fields. The purpose of a good review is to supply reasoned and developed arguments, which is an indispensable ingredient in ...
Sholeh Arastoopoor
doaj  

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Facial Expression Recognition Using Computer Vision: A Systematic Review

open access: yesApplied Sciences, 2019
Emotion recognition has attracted major attention in numerous fields because of its relevant applications in the contemporary world: marketing, psychology, surveillance, and entertainment are some examples.
Daniel Canedo, António J. R. Neves
doaj   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

The Effect of Music on Heart Rate Variability (Review)

open access: yesActa Medica Martiniana, 2021
Music therapy and the use of music in medical practice have now become rapidly advancing and promising areas of non-invasive alternative medicine. However, the opinions of physicians and therapists on the implementation of this complementary therapy ...
Parizek D   +4 more
doaj   +1 more source

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