Results 51 to 60 of about 6,154,854 (261)

SMARCA4-Directed Treatment in Oncology Clinical Trials: A Review [PDF]

open access: yesJournal of Immunotherapy and Precision Oncology
SMARCA4 is an ATPase subunit in the switch/sucrose non-fermentable complex (SWI/SNF), a chromatin-remodeling complex. SMARCA4 provides energy for the SWI/SNF complex to regulate gene expression through chromatin structural rearrangement and transcription
Sarah Hendee, Gerald Falchook
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effectiveness of anterior latissimus dorsi and teres major tendon transfers from subscapularis and anterosuperior cuff tears to reverse shoulder arthroplasty: a narrative review

open access: yesJSES Reviews, Reports, and Techniques
Managing of rotator cuff tears, particularly those involving the subscapularis (SSC), anterosuperior cuff, and massive cuff tears with SSC insufficiency, presents significant clinical challenges.
Chang Hee Baek, MD   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The top 50 most cited articles on superior capsular reconstruction: a bibliometric analysis

open access: yesJSES Reviews, Reports, and Techniques
Background: Bibliometric analysis has been used to quantify and assess a scientific publication and its impact. The purpose of this study was to identify and review the top 50 most cited articles discussing superior capsular reconstruction (SCR). Methods:
Mallery Zeiman, BS   +3 more
doaj   +1 more source

“What language does global business speak?” – The concept and development of BELF [PDF]

open access: yesIbérica, 2013
This paper focuses on the development of the concept of BELF, which originally stood for “Business English as Lingua Franca”, but later we have used the abbreviation to refer to “English as Business Lingua Franca”.
Anne Kankaanranta   +1 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

An explorative study on document type assignment of review articles in Web of Science, Scopus and journals’ websites

open access: yesJournal of Data and Information Science
Accurately assigning the document type of review articles in citation index databases like Web of Science(WoS) and Scopus is important. This study aims to investigate the document type assignation of review articles in Web of Science, Scopus and ...
Zhu Manman   +4 more
doaj   +1 more source

How to Trick Your Opponent: A Review Article on Deceptive Actions in Interactive Sports

open access: yesFrontiers in Psychology, 2017
Performing deceptive actions is a wide-spread phenomenon in sports and it is of considerable practical relevance to know whether or not a fake or a disguised action decreases the opponents’ performance.
Iris Güldenpenning   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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