Results 31 to 40 of about 87,137,076 (257)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This review article examines the effectiveness of psychological therapies in reducing social stigma among patients with a new stoma. The synthesis of findings from multiple studies published within the last five years reveals the significant impact of ...
Nguyen Thi Thuy Nga
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Review article: The art of making mutual benefit through saving time
Review articles are considered to act as a solution for the information overload problem, especially in different scientific fields. The purpose of a good review is to supply reasoned and developed arguments, which is an indispensable ingredient in ...
Sholeh Arastoopoor
doaj
The article provides an overview of the scientific conference “Vectors and Prospects of Describing Cultural Semantics” held on May 25, 2023 at the Pushkin State Institute of the Russian Language within the framework of the Third Kostomarov Forum.
I.A. Skvortsova
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Scope and Meaning of Reasonableness Review After Vavilov [PDF]
This article examines the scope and meaning of reasonableness review in Canadian administrative law, revisiting themes first discussed in the author’s 2015 article.
Daly, Paul
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Shade Selection, a Key to Esthetics
One of the most difficult steps in restorative dentistry can be precisely matching natural teeth with an artificial restoration. Natural teeth come in a variety of shapes and hues.
Shruti Deepak Jadhav +5 more
doaj +1 more source
Simplification or Semantics? Evaluating Vavilov\u27s Impact on Standard of Review [PDF]
The Supreme Court of Canada’s pivotal decision in Canada (Minister of Citizenship and Immigration) v. Vavilov introduced a categorical approach to standard of review analysis, aiming to simplify the existing framework.
Warchuk, Paul A
core +1 more source

