Results 81 to 90 of about 29,295,499 (335)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

is the brain a computer

open access: yesمجلة كلية الطب, 2006
Background:
hussain rustam
doaj  

The Issue of Infant Mortality in Polish Historical Research

open access: yesPrzeszłość Demograficzna Polski, 2020
The article presents infant mortality in Polish historical research and points towards more important works focusing on the above issue. The author analyses approximately seventy academic works in order to answer the fundamental question as to what ...
Dawid Dziuba
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The importance of education on disasters and emergencies: A review article

open access: yesJournal of Education and Health Promotion, 2019
Disasters and emergencies have been increasing all over the world. Todays, with technological advancement, acquiring knowledge and its application in the realm of action is regarded as the only effective way for prevent disasters or reducing its effects.
Sogand Torani   +4 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Hemostasis in laparoscopic renal surgery

open access: yesIndian Journal of Urology, 2012
Hemorrhage is a potential risk at any step of laparoscopic nephrectomies (LNs). The advances in surgical equipment and tissue sealants have increased the safety and efficiency of performing LN and laparoscopic partial nephrectomy (LPN).
Hussam A Hassouna, Ramaswamy Manikandan
doaj   +1 more source

معیارهای تعیین‌کننده بیمارستان سبز: مرور حوزه‌ای

open access: yesمدیریت اطلاعات سلامت, 2020
مقدمه: بیمارستان سبز در جهت صرفه‌جویی منابع و انرژی، منجر به افزایش رقابت‌پذیری، بهره‌وری و کاهش هزینه‌ها می‌گردد. پژوهش حاضر با هدف شناسایی و دسته‌بندی معیارهای تعیین‌کننده بیمارستان سبز انجام شد.
Diba Norozi   +2 more
doaj   +1 more source

Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article

open access: yesEuropean journal of obstetrics & gynecology and reproductive biology: X, 2019
Polycystic ovary syndrome (PCOS) is a heterogeneous condition which is related to an endocrine reproductive disorder of females. It affects females of 18–44 age.
Nida Ajmal   +2 more
semanticscholar   +1 more source

Review Article: Shakespeare and Perception [PDF]

open access: yes, 2014
This article reads some familiar speeches from key Shakespeare plays in the light of modern theories of perception, asking the Shakespeare texts for advice on such matters as “inattentional blindness,” “the distribution of the sensible,” visual ...
Holderness, G.
core   +1 more source

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