Results 61 to 70 of about 37,065,244 (274)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Review paper Post-Lyme disease syndrome
Rheumatology, 2015 About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment.
Joanna Ścieszka +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Review Paper on Transmitarray Antennas
IEEE Access, 2019 This paper presents a thorough review of transmitarray devices particularly aiming antenna beamsteering, gathering some of the most relevant solutions published by the scientific community in the field.
Joao R. Reis +2 more
doaj +1 more source
Submission to the Digital Agenda Review Issues Paper [PDF]
, 2003 The objectives of the Digital Agenda Act were primarily to facilitate the efficient operation of copyright industries online and to promote certainty for the communications and information technology industries.
Rimmer, Matthew, Omar, Ishtiaque
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Writing the literature review for empirical papers
Production, 2018 Paper aims The purpose of the paper is to offer guidance regarding how to write a Literature Review for empirical papers, that provides adequate background and convincing support.
Davi Nakano, Jorge Muniz Jr.
doaj +1 more source
Partisan Review, Volume 32, Number 2, Spring 1965 [PDF]
, 1965 This issue of Partisan Review, Volume 32, Number 2, published in Spring 1965, is a literary and cultural journal featuring essays, interviews, and reviews.
Partisan Review Editors
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source